Early lung disease in infants and preschool children with cystic fibrosis: What have we learned and what should we do about it?
© Copyright 2017 by the American Thoracic Society. The past decade has seen significant advances in understanding of the pathogenesis and progression of lung disease in cystic fibrosis (CF). Pulmonary inflammation, infection, and structural lung damage manifest very early in life and are prevalent a...
| Main Authors: | , , , , |
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| Format: | Journal Article |
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American Thoracic Society
2017
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| Online Access: | http://hdl.handle.net/20.500.11937/54193 |
| _version_ | 1848759307730944000 |
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| author | Ranganathan, S. Hall, Graham Sly, P. Stick, S. Douglas, T. |
| author_facet | Ranganathan, S. Hall, Graham Sly, P. Stick, S. Douglas, T. |
| author_sort | Ranganathan, S. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | © Copyright 2017 by the American Thoracic Society. The past decade has seen significant advances in understanding of the pathogenesis and progression of lung disease in cystic fibrosis (CF). Pulmonary inflammation, infection, and structural lung damage manifest very early in life and are prevalent among preschool children and infants, often in the absence of symptoms or signs. Early childhood represents a pivotal period amenable to intervention strategies that could delay or prevent the onset of lung damage and alter the longer-term clinical trajectory for individuals with CF. This review summarizes what we have learned about early lung disease in children with CF and discusses the implications for future clinical practice and research. |
| first_indexed | 2025-11-14T09:57:48Z |
| format | Journal Article |
| id | curtin-20.500.11937-54193 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T09:57:48Z |
| publishDate | 2017 |
| publisher | American Thoracic Society |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-541932017-09-13T15:49:49Z Early lung disease in infants and preschool children with cystic fibrosis: What have we learned and what should we do about it? Ranganathan, S. Hall, Graham Sly, P. Stick, S. Douglas, T. © Copyright 2017 by the American Thoracic Society. The past decade has seen significant advances in understanding of the pathogenesis and progression of lung disease in cystic fibrosis (CF). Pulmonary inflammation, infection, and structural lung damage manifest very early in life and are prevalent among preschool children and infants, often in the absence of symptoms or signs. Early childhood represents a pivotal period amenable to intervention strategies that could delay or prevent the onset of lung damage and alter the longer-term clinical trajectory for individuals with CF. This review summarizes what we have learned about early lung disease in children with CF and discusses the implications for future clinical practice and research. 2017 Journal Article http://hdl.handle.net/20.500.11937/54193 10.1164/rccm.201606-1107CI American Thoracic Society restricted |
| spellingShingle | Ranganathan, S. Hall, Graham Sly, P. Stick, S. Douglas, T. Early lung disease in infants and preschool children with cystic fibrosis: What have we learned and what should we do about it? |
| title | Early lung disease in infants and preschool children with cystic fibrosis: What have we learned and what should we do about it? |
| title_full | Early lung disease in infants and preschool children with cystic fibrosis: What have we learned and what should we do about it? |
| title_fullStr | Early lung disease in infants and preschool children with cystic fibrosis: What have we learned and what should we do about it? |
| title_full_unstemmed | Early lung disease in infants and preschool children with cystic fibrosis: What have we learned and what should we do about it? |
| title_short | Early lung disease in infants and preschool children with cystic fibrosis: What have we learned and what should we do about it? |
| title_sort | early lung disease in infants and preschool children with cystic fibrosis: what have we learned and what should we do about it? |
| url | http://hdl.handle.net/20.500.11937/54193 |