Evolution of Australian Percutaneous Coronary Intervention (from the Melbourne Interventional Group [MIG] Registry)

Percutaneous coronary intervention (PCI) continues to evolve with shifting patient demographics, treatments, and outcomes. We sought to document the specific changes observed over a 9-year period in a contemporary Australian PCI cohort. The Melbourne Interventional Group is an established multicente...

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Main Authors: Yeoh, J., Yudi, M., Andrianopoulos, N., Yan, B., Clark, D., Duffy, S., Brennan, A., New, G., Freeman, M., Eccleston, D., Sebastian, M., Reid, Christopher, Wilson, W., Ajani, A.
Format: Journal Article
Published: Excerpta Medica, Inc 2017
Online Access:http://hdl.handle.net/20.500.11937/53819
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author Yeoh, J.
Yudi, M.
Andrianopoulos, N.
Yan, B.
Clark, D.
Duffy, S.
Brennan, A.
New, G.
Freeman, M.
Eccleston, D.
Sebastian, M.
Reid, Christopher
Wilson, W.
Ajani, A.
author_facet Yeoh, J.
Yudi, M.
Andrianopoulos, N.
Yan, B.
Clark, D.
Duffy, S.
Brennan, A.
New, G.
Freeman, M.
Eccleston, D.
Sebastian, M.
Reid, Christopher
Wilson, W.
Ajani, A.
author_sort Yeoh, J.
building Curtin Institutional Repository
collection Online Access
description Percutaneous coronary intervention (PCI) continues to evolve with shifting patient demographics, treatments, and outcomes. We sought to document the specific changes observed over a 9-year period in a contemporary Australian PCI cohort. The Melbourne Interventional Group is an established multicenter PCI registry in Melbourne, Australia. Data were collected prospectively with 30-day and 12-month follow-ups. Demographic, procedural, and outcome data for all consecutive patients were analyzed with a year-to-year comparison from 2005 to 2013. National Death Index linkage was performed for long-term mortality analysis; 19,858 procedures were captured over 9 years. Patient complexity and acuity increased with a higher proportion of traditional risk factors and more elderly patients who underwent PCI. Angiographic lesion complexity increased with more multivessel coronary artery disease and more American College of Cardiology/American Heart Association type B2/C lesions proceeding to PCI. The 30-day rate of death, myocardial infarction, or target vessel revascularization has not changed nor has 12-month mortality, myocardial infarction, or major adverse cardiovascular event rates. The strongest independent predictor of long-term mortality was cardiogenic shock at presentation (hazard ratio [HR] 2.95, p <0.01). Drug-eluting stent use (HR 0.83, p <0.01) and a history of dyslipidemia (HR 0.81, p <0.01) were associated with long-term survival. In conclusion, from 2005 to 2013, we observed a cohort of higher risk clinical and angiographic characteristics, with stable long-term mortality.
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spelling curtin-20.500.11937-538192017-10-09T04:04:26Z Evolution of Australian Percutaneous Coronary Intervention (from the Melbourne Interventional Group [MIG] Registry) Yeoh, J. Yudi, M. Andrianopoulos, N. Yan, B. Clark, D. Duffy, S. Brennan, A. New, G. Freeman, M. Eccleston, D. Sebastian, M. Reid, Christopher Wilson, W. Ajani, A. Percutaneous coronary intervention (PCI) continues to evolve with shifting patient demographics, treatments, and outcomes. We sought to document the specific changes observed over a 9-year period in a contemporary Australian PCI cohort. The Melbourne Interventional Group is an established multicenter PCI registry in Melbourne, Australia. Data were collected prospectively with 30-day and 12-month follow-ups. Demographic, procedural, and outcome data for all consecutive patients were analyzed with a year-to-year comparison from 2005 to 2013. National Death Index linkage was performed for long-term mortality analysis; 19,858 procedures were captured over 9 years. Patient complexity and acuity increased with a higher proportion of traditional risk factors and more elderly patients who underwent PCI. Angiographic lesion complexity increased with more multivessel coronary artery disease and more American College of Cardiology/American Heart Association type B2/C lesions proceeding to PCI. The 30-day rate of death, myocardial infarction, or target vessel revascularization has not changed nor has 12-month mortality, myocardial infarction, or major adverse cardiovascular event rates. The strongest independent predictor of long-term mortality was cardiogenic shock at presentation (hazard ratio [HR] 2.95, p <0.01). Drug-eluting stent use (HR 0.83, p <0.01) and a history of dyslipidemia (HR 0.81, p <0.01) were associated with long-term survival. In conclusion, from 2005 to 2013, we observed a cohort of higher risk clinical and angiographic characteristics, with stable long-term mortality. 2017 Journal Article http://hdl.handle.net/20.500.11937/53819 10.1016/j.amjcard.2017.03.258 Excerpta Medica, Inc restricted
spellingShingle Yeoh, J.
Yudi, M.
Andrianopoulos, N.
Yan, B.
Clark, D.
Duffy, S.
Brennan, A.
New, G.
Freeman, M.
Eccleston, D.
Sebastian, M.
Reid, Christopher
Wilson, W.
Ajani, A.
Evolution of Australian Percutaneous Coronary Intervention (from the Melbourne Interventional Group [MIG] Registry)
title Evolution of Australian Percutaneous Coronary Intervention (from the Melbourne Interventional Group [MIG] Registry)
title_full Evolution of Australian Percutaneous Coronary Intervention (from the Melbourne Interventional Group [MIG] Registry)
title_fullStr Evolution of Australian Percutaneous Coronary Intervention (from the Melbourne Interventional Group [MIG] Registry)
title_full_unstemmed Evolution of Australian Percutaneous Coronary Intervention (from the Melbourne Interventional Group [MIG] Registry)
title_short Evolution of Australian Percutaneous Coronary Intervention (from the Melbourne Interventional Group [MIG] Registry)
title_sort evolution of australian percutaneous coronary intervention (from the melbourne interventional group [mig] registry)
url http://hdl.handle.net/20.500.11937/53819