Liver-mediated shedding of platelet GPVI
The in vivo mechanisms underlying antibody-based shedding of the key platelet collagen receptor glycoprotein VI (GPVI) are potentially significant for future antibody-based thromboprotective agents. In this issue of Blood, Stegner et al reveal how the inhibitory Fc receptor, Fc g RIIB, on mouse li...
| Main Authors: | , |
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| Format: | Journal Article |
| Published: |
American Society of Hematology
2016
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| Online Access: | http://hdl.handle.net/20.500.11937/53319 |
| _version_ | 1848759115676909568 |
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| author | Berndt, Michael Andrews, R. |
| author_facet | Berndt, Michael Andrews, R. |
| author_sort | Berndt, Michael |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | The in vivo mechanisms underlying antibody-based shedding of the key platelet collagen receptor glycoprotein VI (GPVI) are potentially significant for future antibody-based thromboprotective agents. In this issue of Blood, Stegner et al reveal how the inhibitory Fc receptor, Fc g RIIB, on mouse liver sinusoidal endothelium mediates both antibody-induced GPVI shedding and entrapment of platelets in the liver. |
| first_indexed | 2025-11-14T09:54:45Z |
| format | Journal Article |
| id | curtin-20.500.11937-53319 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T09:54:45Z |
| publishDate | 2016 |
| publisher | American Society of Hematology |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-533192017-10-24T07:02:46Z Liver-mediated shedding of platelet GPVI Berndt, Michael Andrews, R. The in vivo mechanisms underlying antibody-based shedding of the key platelet collagen receptor glycoprotein VI (GPVI) are potentially significant for future antibody-based thromboprotective agents. In this issue of Blood, Stegner et al reveal how the inhibitory Fc receptor, Fc g RIIB, on mouse liver sinusoidal endothelium mediates both antibody-induced GPVI shedding and entrapment of platelets in the liver. 2016 Journal Article http://hdl.handle.net/20.500.11937/53319 10.1182/blood-2016-07-723973 American Society of Hematology unknown |
| spellingShingle | Berndt, Michael Andrews, R. Liver-mediated shedding of platelet GPVI |
| title | Liver-mediated shedding of platelet GPVI |
| title_full | Liver-mediated shedding of platelet GPVI |
| title_fullStr | Liver-mediated shedding of platelet GPVI |
| title_full_unstemmed | Liver-mediated shedding of platelet GPVI |
| title_short | Liver-mediated shedding of platelet GPVI |
| title_sort | liver-mediated shedding of platelet gpvi |
| url | http://hdl.handle.net/20.500.11937/53319 |