Toll-like receptor 7 and 8 polymorphisms: Associations with functional effects and cellular and antibody responses to measles virus and vaccine

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Toll-like receptor 7 and 8 polymorphisms: Associations with functional effects and cellular and antibody responses to measles virus and vaccine

Successful defence against viral pathogens requires the rapid recognition of virus-specific "danger signals" and the activation of both innate and adaptive immunity. Toll-like receptors (TLR) 7 and 8 play a critical role in the elimination of viruses by recognising the common viral compone...

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Bibliographic Details
Main Authors:	Clifford, H., Yerkovich, S., Khoo, S., Zhang, Guicheng, Upham, J., Le Souëf, P., Richmond, P., Hayden, C.
Format:	Journal Article
Published:	2012
Online Access:	http://hdl.handle.net/20.500.11937/5291

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