HFE p.C282Y homozygosity predisposes to rapid serum ferritin rise after menopause: A genotype-stratified cohort study of hemochromatosis in Australian women

QR Code

HFE p.C282Y homozygosity predisposes to rapid serum ferritin rise after menopause: A genotype-stratified cohort study of hemochromatosis in Australian women

Background and Aim: Women who are homozygous for the p.C282Y mutation in the HFE gene are at much lower risk of iron overload-related disease than p.C282Y homozygous men, presumably because of the iron-depleting effects of menstruation and pregnancy. We used data from a population cohort study to mo...

Full description

Bibliographic Details
Main Authors:	Warne, C., Zaloumis, S., Bertalli, N., Delatycki, M., Nicoll, A., McLaren, C., Hopper, J., Giles, G., Anderson, G., Olynyk, John, Powell, L., Allen, K., Gurrin, L., Bahlo, M., Fletcher, A., Forrest, S., Osborne, N., Vulpe, C., Turkovic, L.
Format:	Journal Article
Published:	Wiley-Blackwell Publishing Asia 2017
Online Access:	http://hdl.handle.net/20.500.11937/52712

Similar Items

The Natural History of Serum Iron Indices for HFE C282Y Homozygosity Associated With Hereditary Hemochromatosis
by: Gurrin, L., et al.
Published: (2008)

HFE C282Tyr homozygotes with serum ferritin concentrations below 100ug/L are at low risk of hemochromatosis
by: Allen, K., et al.
Published: (2010)

HFE C282Y/H63D Compound Heterozygotes Are at Low Risk of Hemochromatosis-Related Morbidity
by: Gurrin, L., et al.
Published: (2009)

Natural history of HFE simple heterozygosity for C282Y and H63D: A prospective 12-year study
by: Zaloumis, S., et al.
Published: (2015)

Iron-overload-related disease in HFE hereditary hemochromatosis
by: Allen, K., et al.
Published: (2008)

HFE C282Y homozygotes are at increased risk of breast and colorectal cancer
by: Osborne, N., et al.
Published: (2010)

A novel association between a SNP in CYBRD1 and serum ferritin levels in a cohort study of HFE hereditary haemochromatosis
by: Constantine, C., et al.
Published: (2009)

Natural history and management of HFE hemochromatosis
by: Gan, E., et al.
Published: (2011)

Should HFE p.C282Y homozygotes with moderately elevated serum ferritin be treated? A randomised controlled trial comparing iron reduction with sham treatment (Mi-iron)
by: Ong, S., et al.
Published: (2015)

Hereditary hemochromatosis in the post-HFE era
by: Olynyk, John, et al.
Published: (2008)

Population-based study of the relationship between mutations in the hemochromatosis (HFE) gene and arthritis
by: Sherrington, C., et al.
Published: (2006)

Letter: Reduced mortality due to phlebotomy in moderately iron-loaded HFE haemochromatosis? The need for clinical trials
by: Delatycki, M., et al.
Published: (2015)

Changes in Brain Transcripts Related to Alzheimer’s Disease in a Model of HFE Hemochromatosis are not Consistent with Increased Alzheimer’s Disease Risk
by: Johnstone, D., et al.
Published: (2012)

The C282Y polymorphism of the hereditary hemochromatosis gene is associated with increased sex hormone-binding globulin and normal testosterone levels in men.
by: Yeap, B., et al.
Published: (2010)

Reduction of body iron in HFE-related haemochromatosis and moderate iron overload (Mi-Iron): a multicentre, participant-blinded, randomised controlled trial
by: Ong, S., et al.
Published: (2017)

A comparison of self-reported and record-linked blood donation history in an Australian cohort
by: Bertalli, N., et al.
Published: (2011)

Low body condition predisposes cattle to lameness: An 8-year study of one dairy herd
by: Rndall, L.V, et al.
Published: (2015)

Clinical perspectives on hereditary hemochromatosis
by: Ayonrinde, O., et al.
Published: (2008)

Pediatric rhinosinusitis: its predisposing factors and management
by: Subha, Sethu Thakachy
Published: (2024)

Characteristics of the arthropathy described in hereditary hemochromatosis
by: Carroll, G., et al.
Published: (2012)

Climatological and socioeconomic factors that predispose to the risk of malaria in Sudan
by: Mohammed, Ibrahim Musa Hassan
Published: (2012)

HFE gene polymorphisms in Malays
by: Jatta, Francis
Published: (2020)

Genetics of hereditary hemochromatosis: A clinical perspective
by: Gan, E., et al.
Published: (2009)

The Role of Hfe in Transferrin-Bound Iron Uptake by Hepatocytes
by: Chua, A., et al.
Published: (2008)

Investigation into the severity of factors predisposing construction projects to risks in Nigeria
by: Adedokun, Olufisayo Adewumi, et al.
Published: (2019)

Mat 282- Pengiraan Kejuruteraan I
by: PPSM, Pusat Pengajian Sains Matematik
Published: (2004)

Detection of HFE Haemochromatosis in the clinic and community using standard erythrocyte tests
by: Adris, N., et al.
Published: (2018)

Evaluation of serum ferritin as a marker of iron status in young Australian adults
by: Mckinnon, E., et al.
Published: (2014)

Doctor shopping behaviour and its predisposing factors amongst dermatology patients
by: Fauzee Andylim, Nizafaziasyida, et al.
Published: (2018)

Doctor shopping behaviour and its predisposing factors amongst dermatology patients
by: Nizafaziasyida Fauzee Andylim,, et al.
Published: (2018)

Elevated serum ferritin: What should GPs know?
by: Goot, K., et al.
Published: (2012)

Rapid ferritin iron release using FMN reductase
by: Lai, Mei I., et al.
Published: (2015)

Novel assay for efficient iron release from ferritin
by: Lim, Wai Feng, et al.
Published: (2014)

Non-Hfe iron overload: Is phlebotomy the answer?
by: Hazeldine, S., et al.
Published: (2013)

Born from pre-eclamptic pregnancies predisposes infants to altered cortisol metabolism in the first postnatal year
by: Broughton Pipkin, Fiona, et al.
Published: (2015)

Effects of HFE gene mutations and alcohol on iron status, liver biochemistry and morbidity
by: Olynyk, John, et al.
Published: (2011)

Determinants of safety behaviors: the mediating effect of predisposing factors / Siti Farhana Hasanudin
by: Hasanudin, Siti Farhana
Published: (2014)

Brain transcriptome perturbations in the Hfe -/- mouse model of genetic iron loading
by: Johnstone, D., et al.
Published: (2012)

ZAE 282/3 - SAINS BAHAN SEPT 1997.
by: PPSF, Pusat Pengajian Sains Fizik
Published: (1997)

ZAE282-3 - MATERIAL SCIENCES - NOVEMBER 2008.
by: PPSF, Pusat Pengajian Sains Fizik
Published: (2008)