Calcium ions as bioinspired triggers to reversibly control the coil-to-helix transition in peptide-polymer conjugates
Controlling a coil-to-helix transition in peptide-polymer conjugates with soft stimuli requires the careful balancing of stabilizing and destabilizing effects in the peptide segment. The transition between two secondary structures of a bioconjugate is realized using calcium ions to establish a biomi...
| Main Authors: | , , |
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| Format: | Journal Article |
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RSC Publishing
2011
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| Online Access: | http://hdl.handle.net/20.500.11937/52637 |
| _version_ | 1848758975688867840 |
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| author | Kühnle, R. Gebauer, Denis Börner, H. |
| author_facet | Kühnle, R. Gebauer, Denis Börner, H. |
| author_sort | Kühnle, R. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Controlling a coil-to-helix transition in peptide-polymer conjugates with soft stimuli requires the careful balancing of stabilizing and destabilizing effects in the peptide segment. The transition between two secondary structures of a bioconjugate is realized using calcium ions to establish a biomimetic control mechanism. Regulation of Ca 2+-ion levels via competitive Ca 2+-ion binders made the process reversible. © 2011 The Royal Society of Chemistry. |
| first_indexed | 2025-11-14T09:52:32Z |
| format | Journal Article |
| id | curtin-20.500.11937-52637 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T09:52:32Z |
| publishDate | 2011 |
| publisher | RSC Publishing |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-526372017-09-13T15:39:04Z Calcium ions as bioinspired triggers to reversibly control the coil-to-helix transition in peptide-polymer conjugates Kühnle, R. Gebauer, Denis Börner, H. Controlling a coil-to-helix transition in peptide-polymer conjugates with soft stimuli requires the careful balancing of stabilizing and destabilizing effects in the peptide segment. The transition between two secondary structures of a bioconjugate is realized using calcium ions to establish a biomimetic control mechanism. Regulation of Ca 2+-ion levels via competitive Ca 2+-ion binders made the process reversible. © 2011 The Royal Society of Chemistry. 2011 Journal Article http://hdl.handle.net/20.500.11937/52637 10.1039/c1sm05625e RSC Publishing restricted |
| spellingShingle | Kühnle, R. Gebauer, Denis Börner, H. Calcium ions as bioinspired triggers to reversibly control the coil-to-helix transition in peptide-polymer conjugates |
| title | Calcium ions as bioinspired triggers to reversibly control the coil-to-helix transition in peptide-polymer conjugates |
| title_full | Calcium ions as bioinspired triggers to reversibly control the coil-to-helix transition in peptide-polymer conjugates |
| title_fullStr | Calcium ions as bioinspired triggers to reversibly control the coil-to-helix transition in peptide-polymer conjugates |
| title_full_unstemmed | Calcium ions as bioinspired triggers to reversibly control the coil-to-helix transition in peptide-polymer conjugates |
| title_short | Calcium ions as bioinspired triggers to reversibly control the coil-to-helix transition in peptide-polymer conjugates |
| title_sort | calcium ions as bioinspired triggers to reversibly control the coil-to-helix transition in peptide-polymer conjugates |
| url | http://hdl.handle.net/20.500.11937/52637 |