The multiple effects of amino acids on the early stages of calcium carbonate crystallization
Proteins have found their way into many of Nature's structures due to their structural stability, diversity in function and composition, and ability to be regulated as well as be regulators themselves. In this study, we investigate the constitutive amino acids that make up some of these protein...
| Main Authors: | , , , , |
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| Format: | Conference Paper |
| Published: |
2012
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| Online Access: | http://hdl.handle.net/20.500.11937/52590 |
| _version_ | 1848758964017168384 |
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| author | Picker, A. Kellermeier, M. Seto, J. Gebauer, Denis Cölfen, H. |
| author_facet | Picker, A. Kellermeier, M. Seto, J. Gebauer, Denis Cölfen, H. |
| author_sort | Picker, A. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Proteins have found their way into many of Nature's structures due to their structural stability, diversity in function and composition, and ability to be regulated as well as be regulators themselves. In this study, we investigate the constitutive amino acids that make up some of these proteins which are involved in CaCO3 mineralization - either in nucleation, crystal growth, or inhibition processes. By assaying all 20 amino acids with vapor diffusion and in situ potentiometric titration, we have found specific amino acids having multiple effects on the early stages of CaCO3 crystallization. These same amino acids have been independently implicated as constituents in liquid- like precursors that form mineralized tissues, processes believed to be key effects of biomineralization proteins in several biological model systems. |
| first_indexed | 2025-11-14T09:52:21Z |
| format | Conference Paper |
| id | curtin-20.500.11937-52590 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T09:52:21Z |
| publishDate | 2012 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-525902023-02-22T06:24:25Z The multiple effects of amino acids on the early stages of calcium carbonate crystallization Picker, A. Kellermeier, M. Seto, J. Gebauer, Denis Cölfen, H. Proteins have found their way into many of Nature's structures due to their structural stability, diversity in function and composition, and ability to be regulated as well as be regulators themselves. In this study, we investigate the constitutive amino acids that make up some of these proteins which are involved in CaCO3 mineralization - either in nucleation, crystal growth, or inhibition processes. By assaying all 20 amino acids with vapor diffusion and in situ potentiometric titration, we have found specific amino acids having multiple effects on the early stages of CaCO3 crystallization. These same amino acids have been independently implicated as constituents in liquid- like precursors that form mineralized tissues, processes believed to be key effects of biomineralization proteins in several biological model systems. 2012 Conference Paper http://hdl.handle.net/20.500.11937/52590 10.1524/zkri.2012.1569 unknown |
| spellingShingle | Picker, A. Kellermeier, M. Seto, J. Gebauer, Denis Cölfen, H. The multiple effects of amino acids on the early stages of calcium carbonate crystallization |
| title | The multiple effects of amino acids on the early stages of calcium carbonate crystallization |
| title_full | The multiple effects of amino acids on the early stages of calcium carbonate crystallization |
| title_fullStr | The multiple effects of amino acids on the early stages of calcium carbonate crystallization |
| title_full_unstemmed | The multiple effects of amino acids on the early stages of calcium carbonate crystallization |
| title_short | The multiple effects of amino acids on the early stages of calcium carbonate crystallization |
| title_sort | multiple effects of amino acids on the early stages of calcium carbonate crystallization |
| url | http://hdl.handle.net/20.500.11937/52590 |