Inversion-based propofol dosing for intravenous induction of hypnosis

© 2016 Elsevier B.V.In this paper we propose an inversion-based methodology for the computation of a feedforward action for the propofol intravenous administration during the induction of hypnosis in general anesthesia. In particular, the typical initial bolus is substituted with a command signal th...

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Main Authors: Padula, Fabrizio, Ionescu, C., Latronico, N., Paltenghi, M., Visioli, A., Vivacqua, G.
Format: Journal Article
Published: Elsevier 2016
Online Access:http://hdl.handle.net/20.500.11937/52197
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author Padula, Fabrizio
Ionescu, C.
Latronico, N.
Paltenghi, M.
Visioli, A.
Vivacqua, G.
author_facet Padula, Fabrizio
Ionescu, C.
Latronico, N.
Paltenghi, M.
Visioli, A.
Vivacqua, G.
author_sort Padula, Fabrizio
building Curtin Institutional Repository
collection Online Access
description © 2016 Elsevier B.V.In this paper we propose an inversion-based methodology for the computation of a feedforward action for the propofol intravenous administration during the induction of hypnosis in general anesthesia. In particular, the typical initial bolus is substituted with a command signal that is obtained by predefining a desired output and by applying an input-output inversion procedure. The robustness of the method has been tested by considering a set of patients with different model parameters, which is representative of a large population.
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institution Curtin University Malaysia
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last_indexed 2025-11-14T09:50:51Z
publishDate 2016
publisher Elsevier
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spelling curtin-20.500.11937-521972017-09-13T15:40:02Z Inversion-based propofol dosing for intravenous induction of hypnosis Padula, Fabrizio Ionescu, C. Latronico, N. Paltenghi, M. Visioli, A. Vivacqua, G. © 2016 Elsevier B.V.In this paper we propose an inversion-based methodology for the computation of a feedforward action for the propofol intravenous administration during the induction of hypnosis in general anesthesia. In particular, the typical initial bolus is substituted with a command signal that is obtained by predefining a desired output and by applying an input-output inversion procedure. The robustness of the method has been tested by considering a set of patients with different model parameters, which is representative of a large population. 2016 Journal Article http://hdl.handle.net/20.500.11937/52197 10.1016/j.cnsns.2016.04.003 Elsevier restricted
spellingShingle Padula, Fabrizio
Ionescu, C.
Latronico, N.
Paltenghi, M.
Visioli, A.
Vivacqua, G.
Inversion-based propofol dosing for intravenous induction of hypnosis
title Inversion-based propofol dosing for intravenous induction of hypnosis
title_full Inversion-based propofol dosing for intravenous induction of hypnosis
title_fullStr Inversion-based propofol dosing for intravenous induction of hypnosis
title_full_unstemmed Inversion-based propofol dosing for intravenous induction of hypnosis
title_short Inversion-based propofol dosing for intravenous induction of hypnosis
title_sort inversion-based propofol dosing for intravenous induction of hypnosis
url http://hdl.handle.net/20.500.11937/52197