Forearm to fingertip skin temperature gradients in the thermoneutral zone were significantly related to resting metabolic rate: potential implications for nutrition research
© 2017 Macmillan Publishers Limited, part of Springer Nature.Background:Resting metabolic rate (RMR) should be measured in the thermoneutral zone (TNZ). Forearm to fingertip skin temperature gradients (FFG) could serve as an objective measure of this pre-condition.Subjects/Methods:Eighty-six adult A...
| Main Authors: | , , , , , , |
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| Format: | Journal Article |
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Nature Publishing Group
2017
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| Online Access: | http://hdl.handle.net/20.500.11937/52190 |
| _version_ | 1848758867978092544 |
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| author | Pathak, K. Calton, E. Soares, Mario Zhao, Y. James, A. Keane, K. Newsholme, P. |
| author_facet | Pathak, K. Calton, E. Soares, Mario Zhao, Y. James, A. Keane, K. Newsholme, P. |
| author_sort | Pathak, K. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | © 2017 Macmillan Publishers Limited, part of Springer Nature.Background:Resting metabolic rate (RMR) should be measured in the thermoneutral zone (TNZ). Forearm to fingertip skin temperature gradients (FFG) could serve as an objective measure of this pre-condition.Subjects/Methods:Eighty-six adult Australians were studied at 25?°C in a temperature-controlled chamber. Measurements of overnight fasted RMR, respiratory quotient (RQ) and FFG were complemented by clinical biochemistry. McAuley’s Index of insulin sensitivity (McA_ISI) and presence of metabolic syndrome was determined. Physical activity was estimated from the short version of the International Physical Activity Questionnaire. Fat mass (FM) and fat-free mass (FFM) were obtained from dual-energy x-ray absorptiometry. Twenty-nine participants were assessed for changes in RMR (?RMR), RQ (?RQ) and FFG (?FFG) following a 6-month free-living period. Multiple linear regression analyses of RMR and RQ on FFG, and of ?RMR and ?RQ on ?FFG were conducted after controlling for 12 known determinants of energy metabolism.Results:There were wide between-subject variations in unadjusted FFG ranging from -4.25 to +7.8?°C. The final parsimonious model for cross-sectional observations of RMR included age, FM, FFM, McA_ISI and FFG (ß=63 kJ/d (95% confidence interval (CI): 14.2, 112.1, P=0.012)). However, FFG was unrelated to RQ.In the longitudinal cohort, adjusted ?RMR significantly associated only with ?FFG (ß=100?kJ/d (95% CI: 10.3, 189.1; P=0.030)), and adjusted ?RQ associated with ?FFG (-0.003 (95% CI: -0.005, 0.0002, P=0.038)), age and McA_ISI.Conclusions:Sizeable between-subject variations in FFG at 25?°C were associated with RMR and RQ. Monitoring FFG may serve as an objective assessment of the TNZ during RMR measurements.European Journal of Clinical Nutrition advance online publication, 5 April 2017; doi:10.1038/ejcn.2017.30. |
| first_indexed | 2025-11-14T09:50:49Z |
| format | Journal Article |
| id | curtin-20.500.11937-52190 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T09:50:49Z |
| publishDate | 2017 |
| publisher | Nature Publishing Group |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-521902019-02-19T04:27:24Z Forearm to fingertip skin temperature gradients in the thermoneutral zone were significantly related to resting metabolic rate: potential implications for nutrition research Pathak, K. Calton, E. Soares, Mario Zhao, Y. James, A. Keane, K. Newsholme, P. © 2017 Macmillan Publishers Limited, part of Springer Nature.Background:Resting metabolic rate (RMR) should be measured in the thermoneutral zone (TNZ). Forearm to fingertip skin temperature gradients (FFG) could serve as an objective measure of this pre-condition.Subjects/Methods:Eighty-six adult Australians were studied at 25?°C in a temperature-controlled chamber. Measurements of overnight fasted RMR, respiratory quotient (RQ) and FFG were complemented by clinical biochemistry. McAuley’s Index of insulin sensitivity (McA_ISI) and presence of metabolic syndrome was determined. Physical activity was estimated from the short version of the International Physical Activity Questionnaire. Fat mass (FM) and fat-free mass (FFM) were obtained from dual-energy x-ray absorptiometry. Twenty-nine participants were assessed for changes in RMR (?RMR), RQ (?RQ) and FFG (?FFG) following a 6-month free-living period. Multiple linear regression analyses of RMR and RQ on FFG, and of ?RMR and ?RQ on ?FFG were conducted after controlling for 12 known determinants of energy metabolism.Results:There were wide between-subject variations in unadjusted FFG ranging from -4.25 to +7.8?°C. The final parsimonious model for cross-sectional observations of RMR included age, FM, FFM, McA_ISI and FFG (ß=63 kJ/d (95% confidence interval (CI): 14.2, 112.1, P=0.012)). However, FFG was unrelated to RQ.In the longitudinal cohort, adjusted ?RMR significantly associated only with ?FFG (ß=100?kJ/d (95% CI: 10.3, 189.1; P=0.030)), and adjusted ?RQ associated with ?FFG (-0.003 (95% CI: -0.005, 0.0002, P=0.038)), age and McA_ISI.Conclusions:Sizeable between-subject variations in FFG at 25?°C were associated with RMR and RQ. Monitoring FFG may serve as an objective assessment of the TNZ during RMR measurements.European Journal of Clinical Nutrition advance online publication, 5 April 2017; doi:10.1038/ejcn.2017.30. 2017 Journal Article http://hdl.handle.net/20.500.11937/52190 10.1038/ejcn.2017.30 Nature Publishing Group restricted |
| spellingShingle | Pathak, K. Calton, E. Soares, Mario Zhao, Y. James, A. Keane, K. Newsholme, P. Forearm to fingertip skin temperature gradients in the thermoneutral zone were significantly related to resting metabolic rate: potential implications for nutrition research |
| title | Forearm to fingertip skin temperature gradients in the thermoneutral zone were significantly related to resting metabolic rate: potential implications for nutrition research |
| title_full | Forearm to fingertip skin temperature gradients in the thermoneutral zone were significantly related to resting metabolic rate: potential implications for nutrition research |
| title_fullStr | Forearm to fingertip skin temperature gradients in the thermoneutral zone were significantly related to resting metabolic rate: potential implications for nutrition research |
| title_full_unstemmed | Forearm to fingertip skin temperature gradients in the thermoneutral zone were significantly related to resting metabolic rate: potential implications for nutrition research |
| title_short | Forearm to fingertip skin temperature gradients in the thermoneutral zone were significantly related to resting metabolic rate: potential implications for nutrition research |
| title_sort | forearm to fingertip skin temperature gradients in the thermoneutral zone were significantly related to resting metabolic rate: potential implications for nutrition research |
| url | http://hdl.handle.net/20.500.11937/52190 |