PH-Dependent Schemes of Calcium Carbonate Formation in the Presence of Alginates

© 2016 American Chemical Society.From recent studies on bone and shell formation, the importance of polysaccharides in biomineralization processes is gradually being recognized. Through ion-complexation and self-assembly properties, such macromolecules have remarkable effects on mineralization. Howe...

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Main Authors: Rao, A., Vásquez-Quitral, P., Fernández, M., Berg, J., Sánchez, M., Drechsler, M., Neira-Carrillo, A., Arias, J., Gebauer, Denis, Cölfen, H.
Format: Journal Article
Published: American Chemical Society 2016
Online Access:http://hdl.handle.net/20.500.11937/51923
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author Rao, A.
Vásquez-Quitral, P.
Fernández, M.
Berg, J.
Sánchez, M.
Drechsler, M.
Neira-Carrillo, A.
Arias, J.
Gebauer, Denis
Cölfen, H.
author_facet Rao, A.
Vásquez-Quitral, P.
Fernández, M.
Berg, J.
Sánchez, M.
Drechsler, M.
Neira-Carrillo, A.
Arias, J.
Gebauer, Denis
Cölfen, H.
author_sort Rao, A.
building Curtin Institutional Repository
collection Online Access
description © 2016 American Chemical Society.From recent studies on bone and shell formation, the importance of polysaccharides in biomineralization processes is gradually being recognized. Through ion-complexation and self-assembly properties, such macromolecules have remarkable effects on mineralization. However, their influences on the different regimes of crystallization including the interactions with precursor species are unclear. The present study therefore addresses calcium carbonate mineralization in the presence of alginates, a class of linear copolymeric saccharides composed of ß-1,4 linked d-mannuronic and l-guluronic acid. During mineralization, this biopolymer is found to exert pH-dependent control over mineralization pathways in terms of the stability of prenucleation clusters, inhibitory effect toward nucleation and initially formed postnucleation products. Remarkably in the presence of this macromolecular additive, either amorphous or crystalline vaterite particles can be selectively nucleated in a pH-dependent manner. This is validated by electron microscopy wherein vaterite particles are intimately associated with alginate assemblies after nucleation at pH 9.75. At lower pH, aggregates of amorphous particles are formed. Thus, in addition to the general focus on biochemical properties of additives, solution pH, a physiologically fundamental parameter significantly alters the scheme of mineralization.
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spelling curtin-20.500.11937-519232017-09-13T15:40:03Z PH-Dependent Schemes of Calcium Carbonate Formation in the Presence of Alginates Rao, A. Vásquez-Quitral, P. Fernández, M. Berg, J. Sánchez, M. Drechsler, M. Neira-Carrillo, A. Arias, J. Gebauer, Denis Cölfen, H. © 2016 American Chemical Society.From recent studies on bone and shell formation, the importance of polysaccharides in biomineralization processes is gradually being recognized. Through ion-complexation and self-assembly properties, such macromolecules have remarkable effects on mineralization. However, their influences on the different regimes of crystallization including the interactions with precursor species are unclear. The present study therefore addresses calcium carbonate mineralization in the presence of alginates, a class of linear copolymeric saccharides composed of ß-1,4 linked d-mannuronic and l-guluronic acid. During mineralization, this biopolymer is found to exert pH-dependent control over mineralization pathways in terms of the stability of prenucleation clusters, inhibitory effect toward nucleation and initially formed postnucleation products. Remarkably in the presence of this macromolecular additive, either amorphous or crystalline vaterite particles can be selectively nucleated in a pH-dependent manner. This is validated by electron microscopy wherein vaterite particles are intimately associated with alginate assemblies after nucleation at pH 9.75. At lower pH, aggregates of amorphous particles are formed. Thus, in addition to the general focus on biochemical properties of additives, solution pH, a physiologically fundamental parameter significantly alters the scheme of mineralization. 2016 Journal Article http://hdl.handle.net/20.500.11937/51923 10.1021/acs.cgd.5b01488 American Chemical Society restricted
spellingShingle Rao, A.
Vásquez-Quitral, P.
Fernández, M.
Berg, J.
Sánchez, M.
Drechsler, M.
Neira-Carrillo, A.
Arias, J.
Gebauer, Denis
Cölfen, H.
PH-Dependent Schemes of Calcium Carbonate Formation in the Presence of Alginates
title PH-Dependent Schemes of Calcium Carbonate Formation in the Presence of Alginates
title_full PH-Dependent Schemes of Calcium Carbonate Formation in the Presence of Alginates
title_fullStr PH-Dependent Schemes of Calcium Carbonate Formation in the Presence of Alginates
title_full_unstemmed PH-Dependent Schemes of Calcium Carbonate Formation in the Presence of Alginates
title_short PH-Dependent Schemes of Calcium Carbonate Formation in the Presence of Alginates
title_sort ph-dependent schemes of calcium carbonate formation in the presence of alginates
url http://hdl.handle.net/20.500.11937/51923