Targeting macrophages rescues age and tumor-induced T cell dysfunction in elderly mice
| Main Authors: | Jackaman, Connie, Dye, Danielle, Crabb, H., Gardner, J., Grounds, M., Nelson, D. |
|---|---|
| Format: | Conference Paper |
| Published: |
WILEY-BLACKWELL
2016
|
| Online Access: | http://hdl.handle.net/20.500.11937/51832 |
Similar Items
IL-2/CD40-activated macrophages rescue age and tumor-induced T cell dysfunction in elderly mice
by: Jackaman, Connie, et al.
Published: (2014)
by: Jackaman, Connie, et al.
Published: (2014)
Targeting macrophages rescues age-related immune deficiencies in C57BL/6J geriatric mice
by: Jackaman, Connie, et al.
Published: (2013)
by: Jackaman, Connie, et al.
Published: (2013)
Macrophage Depletion in Elderly Mice Improves Response to Tumor Immunotherapy, Increases Anti-tumor T Cell Activity and Reduces Treatment-Induced Cachexia
by: Duong, L., et al.
Published: (2018)
by: Duong, L., et al.
Published: (2018)
Aged neutrophils accumulate in lymphoid tissues from healthy elderly mice and infiltrate T- and B-cell zones
by: Tomay, F., et al.
Published: (2018)
by: Tomay, F., et al.
Published: (2018)
Lipid-laden partially-activated plasmacytoid and CD4-CD8a+ dendritic cells accumulate in tissues in elderly mice
by: Gardner, Joanne, et al.
Published: (2014)
by: Gardner, Joanne, et al.
Published: (2014)
Are macrophages, myeloid derived suppressor cells and neutrophils mediators of local suppression in healthy and cancerous tissues in aging hosts?
by: Jackaman, Connie, et al.
Published: (2013)
by: Jackaman, Connie, et al.
Published: (2013)
Despite generating a weak tumour-specific CTL response during tumour progression chemotherapy is only effective in elderly mice if T cells are present
by: Nelson, D., et al.
Published: (2016)
by: Nelson, D., et al.
Published: (2016)
CD8+ cytotoxic T cell responses to dominant tumor-associated antigens are profoundly weakened by aging yet subdominant responses retain functionality and expand in response to chemotherapy
by: Jackaman, Connie, et al.
Published: (2019)
by: Jackaman, Connie, et al.
Published: (2019)
Aging and cancer: The role of macrophages and neutrophils
by: Jackaman, Connie, et al.
Published: (2017)
by: Jackaman, Connie, et al.
Published: (2017)
Understanding the underlying mechanisms behind macrophage dysfunction in the elderly tumour microenvironment
by: Duong, Lelinh
Published: (2023)
by: Duong, Lelinh
Published: (2023)
Mertk on tumor macrophages is a therapeutic target to prevent tumor recurrence following radiation therapy
by: Crittenden, Marka R., et al.
Published: (2016)
by: Crittenden, Marka R., et al.
Published: (2016)
Murine mesothelioma induces locally-proliferating IL-10+TNF-a+CD206-CX3CR1+ M3 macrophages that can be selectively depleted by chemotherapy or immunotherapy
by: Jackaman, Connie, et al.
Published: (2016)
by: Jackaman, Connie, et al.
Published: (2016)
Aging induces increased expression of checkpoint inhibitory molecules on dendritic cells
by: Gardner, J., et al.
Published: (2016)
by: Gardner, J., et al.
Published: (2016)
Ageing and Mesothelioma Drive Lipid Accumulation and Dysfunction in Dendritic Cells and Macrophages
by: Sheeraz, Mohd
Published: (2022)
by: Sheeraz, Mohd
Published: (2022)
Mesothelioma tumor cells modulate dendritic cell lipid content, phenotype and function
by: Gardner, J., et al.
Published: (2015)
by: Gardner, J., et al.
Published: (2015)
Intratumoral interleukin-2/agonist CD40 antibody drives CD4+-independent resolution of treated-tumors and CD4+-dependent systemic and memory responses
by: Jackaman, Connie, et al.
Published: (2012)
by: Jackaman, Connie, et al.
Published: (2012)
Sarcostemma viminale activates macrophages to a pro-inflammatory phenotype
by: Brestovac, Brian, et al.
Published: (2014)
by: Brestovac, Brian, et al.
Published: (2014)
Breast Tumor Angiogenesis and Tumor-AssociatedMacrophages:
Histopathologist’s Perspective
by: Ewe, Seng Ch’ng, et al.
Published: (2011)
by: Ewe, Seng Ch’ng, et al.
Published: (2011)
CD40-activated B cells contribute to mesothelioma tumor regression
by: Jackaman, Connie, et al.
Published: (2011)
by: Jackaman, Connie, et al.
Published: (2011)
Modulation of dendritic cell and T cell cross-talk during aging: The potential role of checkpoint inhibitory molecules
by: Gardner, J., et al.
Published: (2017)
by: Gardner, J., et al.
Published: (2017)
Blockade of TNF in vivo using cV1q antibody reduces contractile dysfunction of skeletal muscle in response to eccentric exercise in dystrophic mdx and normal mice
by: Piers, A., et al.
Published: (2011)
by: Piers, A., et al.
Published: (2011)
The “Trojan Horse” Approach to Tumor Immunotherapy: Targeting the Tumor Microenvironment
by: Nelson, Delia, et al.
Published: (2014)
by: Nelson, Delia, et al.
Published: (2014)
Blood-brain barrier dysfunction developed during normal aging is associated with inflammation and loss of tight junctions but not with leukocyte recruitment
by: Elahy, Mina, et al.
Published: (2015)
by: Elahy, Mina, et al.
Published: (2015)
The Regulatory Status Adopted by Lymph Node Dendritic Cells and T Cells During Healthy Aging Is Maintained During Cancer and May Contribute to Reduced Responses to Immunotherapy
by: Gardner, J., et al.
Published: (2018)
by: Gardner, J., et al.
Published: (2018)
Chemotherapy broadens the range of tumor antigens seen by cytotoxic CD8+ T cells in vivo
by: Jackaman, Connie, et al.
Published: (2012)
by: Jackaman, Connie, et al.
Published: (2012)
The different impact of a high fat diet on dystrophic mdx and control C57Bl/10 mice
by: Crabb, Hannah, et al.
Published: (2011)
by: Crabb, Hannah, et al.
Published: (2011)
N-Acetylcysteine treatment of dystrophic mdx mice results in protein thiol modifications and inhibition of exercise induced myofibre necrosis
by: Terrill, J., et al.
Published: (2012)
by: Terrill, J., et al.
Published: (2012)
Elderly dendritic cells respond to LPS/IFN-γ and CD40L stimulation despite incomplete maturation
by: Gardner, J., et al.
Published: (2018)
by: Gardner, J., et al.
Published: (2018)
Rapid copper acquisition by developing murine mesothelioma: Decreasing bioavailable copper slows tumor growth, normalizes vessels and promotes T cell infiltration
by: Crowe, Andrew, et al.
Published: (2013)
by: Crowe, Andrew, et al.
Published: (2013)
Intratumoral interleukin-2/agonist CD40 antibody drives CD4+ - independent resolution of treated-turmors and CD4+ -dependent systemic and memory responses
by: Jackaman, Connie, et al.
Published: (2012)
by: Jackaman, Connie, et al.
Published: (2012)
Effects of loaded voluntary wheel exercise on performance and muscle hypertrophy in young and old male C57Bl/6J mice
by: Soffe, Z., et al.
Published: (2016)
by: Soffe, Z., et al.
Published: (2016)
Molecular analyses provide insight into mechanisms underlying sarcopenia and myofibre denervation in old skeletal muscles of mice
by: Barns, M., et al.
Published: (2014)
by: Barns, M., et al.
Published: (2014)
In vivo tumor targeting and anti-tumor effects of 5-fluororacil loaded, folic acid targeted quantum dot system
by: Bwatanglang, Ibrahim Birma, et al.
Published: (2016)
by: Bwatanglang, Ibrahim Birma, et al.
Published: (2016)
Lifelong exercise and locally produced insulin-like growth factor-1 (IGF-1) have a modest influence on reducing age-related muscle wasting in mice
by: McMahon, C., et al.
Published: (2014)
by: McMahon, C., et al.
Published: (2014)
Anti-inflammatory effects of asiaticoside on tumor necrosis factor-α and interferon-ᵧ Induced raw 264.7 macrophage
by: Zainudin, Nurfarahdilla
Published: (2016)
by: Zainudin, Nurfarahdilla
Published: (2016)
Expression of sema4d and its receptor
Plexin-b1 in invasive breast ductal
Carcinoma in relation to
Tumor angiogenesis and
Tumor-associated macrophages
by: Seng,, Ch’ng Ewe
Published: (2012)
by: Seng,, Ch’ng Ewe
Published: (2012)
Effect of Posterior Tibial Nerve Stimulation on Erectile Dysfunction Among Elderly Patients
by: Nilavan, T., et al.
Published: (2023)
by: Nilavan, T., et al.
Published: (2023)
Olfactory Dysfunction is Associated with Subjective Memory Complaints in Community- Dwelling Elderly Individuals
by: Sohrabi, H.R., et al.
Published: (2009)
by: Sohrabi, H.R., et al.
Published: (2009)
A single 30 min treadmill exercise session is suitable for 'proof-of-concept studies' in adult mdx mice: A comparison of the early consequences of two different treadmill protocols.
by: Crabb, Hannah, et al.
Published: (2012)
by: Crabb, Hannah, et al.
Published: (2012)
Bioactive scaffolds in skeletal muscle regeneration and tissue engineering
by: Chaturvedi, Vishal, et al.
Published: (2011)
by: Chaturvedi, Vishal, et al.
Published: (2011)
Similar Items
-
IL-2/CD40-activated macrophages rescue age and tumor-induced T cell dysfunction in elderly mice
by: Jackaman, Connie, et al.
Published: (2014) -
Targeting macrophages rescues age-related immune deficiencies in C57BL/6J geriatric mice
by: Jackaman, Connie, et al.
Published: (2013) -
Macrophage Depletion in Elderly Mice Improves Response to Tumor Immunotherapy, Increases Anti-tumor T Cell Activity and Reduces Treatment-Induced Cachexia
by: Duong, L., et al.
Published: (2018) -
Aged neutrophils accumulate in lymphoid tissues from healthy elderly mice and infiltrate T- and B-cell zones
by: Tomay, F., et al.
Published: (2018) -
Lipid-laden partially-activated plasmacytoid and CD4-CD8a+ dendritic cells accumulate in tissues in elderly mice
by: Gardner, Joanne, et al.
Published: (2014)