New approaches to ancient DNA: using novel substrates to characterise DNA preservation and past biodiversity in warm-climate ecosystems

Retrieving ancient DNA (aDNA) from fossils in warm, tropical environments remains a challenge. This thesis describes the development and application of next generation sequencing technologies in the search for warm-climate aDNA. Methods to extract, enrich and sequence aDNA from fossil ‘bulk bone’ an...

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Bibliographic Details
Main Author: Grealy, Alicia Catherine
Format: Thesis
Published: Curtin University 2016
Online Access:http://hdl.handle.net/20.500.11937/51741
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author Grealy, Alicia Catherine
author_facet Grealy, Alicia Catherine
author_sort Grealy, Alicia Catherine
building Curtin Institutional Repository
collection Online Access
description Retrieving ancient DNA (aDNA) from fossils in warm, tropical environments remains a challenge. This thesis describes the development and application of next generation sequencing technologies in the search for warm-climate aDNA. Methods to extract, enrich and sequence aDNA from fossil ‘bulk bone’ and avian eggshell are successfully explored from sites in Australia and Madagascar. Collectively, the research provides new insights into past biodiversity and evolutionary processes in climates not previously considered conducive to DNA preservation.
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format Thesis
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institution Curtin University Malaysia
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last_indexed 2025-11-14T09:39:15Z
publishDate 2016
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spelling curtin-20.500.11937-517412018-03-05T06:28:23Z New approaches to ancient DNA: using novel substrates to characterise DNA preservation and past biodiversity in warm-climate ecosystems Grealy, Alicia Catherine Retrieving ancient DNA (aDNA) from fossils in warm, tropical environments remains a challenge. This thesis describes the development and application of next generation sequencing technologies in the search for warm-climate aDNA. Methods to extract, enrich and sequence aDNA from fossil ‘bulk bone’ and avian eggshell are successfully explored from sites in Australia and Madagascar. Collectively, the research provides new insights into past biodiversity and evolutionary processes in climates not previously considered conducive to DNA preservation. 2016 Thesis http://hdl.handle.net/20.500.11937/51741 Curtin University fulltext
spellingShingle Grealy, Alicia Catherine
New approaches to ancient DNA: using novel substrates to characterise DNA preservation and past biodiversity in warm-climate ecosystems
title New approaches to ancient DNA: using novel substrates to characterise DNA preservation and past biodiversity in warm-climate ecosystems
title_full New approaches to ancient DNA: using novel substrates to characterise DNA preservation and past biodiversity in warm-climate ecosystems
title_fullStr New approaches to ancient DNA: using novel substrates to characterise DNA preservation and past biodiversity in warm-climate ecosystems
title_full_unstemmed New approaches to ancient DNA: using novel substrates to characterise DNA preservation and past biodiversity in warm-climate ecosystems
title_short New approaches to ancient DNA: using novel substrates to characterise DNA preservation and past biodiversity in warm-climate ecosystems
title_sort new approaches to ancient dna: using novel substrates to characterise dna preservation and past biodiversity in warm-climate ecosystems
url http://hdl.handle.net/20.500.11937/51741