Risk factors for malignant mesothelioma in people with no known exposure to asbestos

Objectives: Malignant mesothelioma (MM) is a rare and generally fatal cancer, usually caused by asbestos, although about 5-10% of cases report no asbestos exposure. This study aimed to identify sources whereby people in Western Australia (WA) may be unknowingly exposed to asbestos or to other exposu...

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Main Authors: Musk, B., Gordon, L., Alfonso, Helman, Reid, Alison, Olsen, N., Mina, R., Franklin, P., Peters, S., Brims, Fraser, Hui, J., de Klerk, N.
Format: Journal Article
Published: 2017
Online Access:http://hdl.handle.net/20.500.11937/51593
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author Musk, B.
Gordon, L.
Alfonso, Helman
Reid, Alison
Olsen, N.
Mina, R.
Franklin, P.
Peters, S.
Brims, Fraser
Hui, J.
de Klerk, N.
author_facet Musk, B.
Gordon, L.
Alfonso, Helman
Reid, Alison
Olsen, N.
Mina, R.
Franklin, P.
Peters, S.
Brims, Fraser
Hui, J.
de Klerk, N.
author_sort Musk, B.
building Curtin Institutional Repository
collection Online Access
description Objectives: Malignant mesothelioma (MM) is a rare and generally fatal cancer, usually caused by asbestos, although about 5-10% of cases report no asbestos exposure. This study aimed to identify sources whereby people in Western Australia (WA) may be unknowingly exposed to asbestos or to other exposures which may cause MM. Methods: Cases with no known asbestos exposure were selected from the WA Mesothelioma Register (WAMR). Matched controls were selected from hospital patients admitted for conditions unrelated to asbestos. Occupational histories were coded by an industrial hygienist. Data were analyzed using conditional logistic regression. Results: Thirty-eight MM participants and 134 controls were recruited. Risk of MM was increased (OR=3.1, 95%CI 1.0-9.6) after no known, but likely, exposure to asbestos at work. Conclusions: Because of its extensive use, few people in WA have never been exposed to asbestos. Unrecognized exposure may cause most MM cases initially regarded as "no exposure."
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spelling curtin-20.500.11937-515932017-09-13T15:46:02Z Risk factors for malignant mesothelioma in people with no known exposure to asbestos Musk, B. Gordon, L. Alfonso, Helman Reid, Alison Olsen, N. Mina, R. Franklin, P. Peters, S. Brims, Fraser Hui, J. de Klerk, N. Objectives: Malignant mesothelioma (MM) is a rare and generally fatal cancer, usually caused by asbestos, although about 5-10% of cases report no asbestos exposure. This study aimed to identify sources whereby people in Western Australia (WA) may be unknowingly exposed to asbestos or to other exposures which may cause MM. Methods: Cases with no known asbestos exposure were selected from the WA Mesothelioma Register (WAMR). Matched controls were selected from hospital patients admitted for conditions unrelated to asbestos. Occupational histories were coded by an industrial hygienist. Data were analyzed using conditional logistic regression. Results: Thirty-eight MM participants and 134 controls were recruited. Risk of MM was increased (OR=3.1, 95%CI 1.0-9.6) after no known, but likely, exposure to asbestos at work. Conclusions: Because of its extensive use, few people in WA have never been exposed to asbestos. Unrecognized exposure may cause most MM cases initially regarded as "no exposure." 2017 Journal Article http://hdl.handle.net/20.500.11937/51593 10.1002/ajim.22695 restricted
spellingShingle Musk, B.
Gordon, L.
Alfonso, Helman
Reid, Alison
Olsen, N.
Mina, R.
Franklin, P.
Peters, S.
Brims, Fraser
Hui, J.
de Klerk, N.
Risk factors for malignant mesothelioma in people with no known exposure to asbestos
title Risk factors for malignant mesothelioma in people with no known exposure to asbestos
title_full Risk factors for malignant mesothelioma in people with no known exposure to asbestos
title_fullStr Risk factors for malignant mesothelioma in people with no known exposure to asbestos
title_full_unstemmed Risk factors for malignant mesothelioma in people with no known exposure to asbestos
title_short Risk factors for malignant mesothelioma in people with no known exposure to asbestos
title_sort risk factors for malignant mesothelioma in people with no known exposure to asbestos
url http://hdl.handle.net/20.500.11937/51593