An azaspirane derivative suppresses growth and induces apoptosis of ER-positive and ER-negative breast cancer cells through the modulation of JAK2/STAT3 signaling pathway

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An azaspirane derivative suppresses growth and induces apoptosis of ER-positive and ER-negative breast cancer cells through the modulation of JAK2/STAT3 signaling pathway

Persistent activation of signal transducer and activator of transcription 3 (STAT3) is associated with the progression of a range of tumors. In this report, we present the anticancer activity of 2-(1-(4-(2-cyanophenyl)1-benzyl1H-indol-3-yl)-5- (4-methoxy-phenyl)-1-oxa-3-azaspiro(5,5)undecane (CIMO)...

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Bibliographic Details
Main Authors:	Sulaiman, N., Mohan, C., Basappa, B., Pandey, V., Rangappa, S., Bharathkumar, H., Kumar, Alan Prem, Lobie, P., Rangappa, K.
Format:	Journal Article
Published:	Spandidos Publications 2016
Online Access:	http://hdl.handle.net/20.500.11937/51573

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