Innovative Microcapsules for Pancreatic ß-Cells Harvested from Mature Double-Transgenic Mice: Cell Imaging, Viability, Induced Glucose-Stimulated Insulin Measurements and Proinflammatory Cytokines Analysis
Purpose: Recently we demonstrated that microencapsulation of a murine pancreatic ß-cell line using an alginate-ursodeoxycholic acid (UDCA) matrix produced microcapsules with good stability and cell viability. In this study, we investigated if translation of this formulation to microencapsulation of...
| Main Authors: | Mooranian, Armin, Takechi, Ryu, Jamieson, E., Morahan, G., Al-Salami, Hani |
|---|---|
| Format: | Journal Article |
| Published: |
AAPS
2017
|
| Online Access: | http://hdl.handle.net/20.500.11937/51500 |
Similar Items
Alginate-combined cholic acid increased insulin secretion of microencapsulated mouse cloned pancreatic ß cells
by: Mooranian, A., et al.
Published: (2017)
by: Mooranian, A., et al.
Published: (2017)
Biological Assessments of Encapsulated Pancreatic ß-Cells: Their Potential Transplantation in Diabetes
by: Mooranian, Armin, et al.
Published: (2016)
by: Mooranian, Armin, et al.
Published: (2016)
Designing anti-diabetic ß-cells microcapsules using polystyrenic sulfonate, polyallylamine and a tertiary bile acid: Morphology, bioenergetics and cytokine analysis.
by: Mooranian, A., et al.
Published: (2016)
by: Mooranian, A., et al.
Published: (2016)
Multicompartmental, multilayered probucol microcapsules for diabetes mellitus: Formulation characterization and effects on production of insulin and inflammation in a pancreatic ß-cell line
by: Mooranian, A., et al.
Published: (2015)
by: Mooranian, A., et al.
Published: (2015)
The effect of molecular weights of microencapsulating polymers on viability of mouse-cloned pancreatic ß-cells: biomaterials, osmotic forces and potential applications in diabetes treatment
by: Mooranian, A., et al.
Published: (2018)
by: Mooranian, A., et al.
Published: (2018)
Electrokinetic potential-stabilization by bile acid-microencapsulating formulation of pancreatic ß-cells cultured in high ratio poly-L-ornithine-gel hydrogel colloidal dispersion: applications in cell-biomaterials, tissue engineering and biotechnological applications
by: Mooranian, A., et al.
Published: (2017)
by: Mooranian, A., et al.
Published: (2017)
Influence of Biotechnological Processes, Speed of Formulation Flow and Cellular Concurrent Stream-Integration on Insulin Production from ß-cells as a Result of Co-Encapsulation with a Highly Lipophilic Bile Acid
by: Mooranian, A., et al.
Published: (2017)
by: Mooranian, A., et al.
Published: (2017)
New biotechnological microencapsulating methodology utilizing individualized gradient-screened jet laminar flow techniques for pancreatic ß-cell delivery: bile acids support cell energy-generating mechanisms
by: Mooranian, A., et al.
Published: (2017)
by: Mooranian, A., et al.
Published: (2017)
Characterization of a novel bile acid-based delivery platform for microencapsulated pancreatic ß-cells.
by: Mooranian, Armin, et al.
Published: (2014)
by: Mooranian, Armin, et al.
Published: (2014)
Viability and topographical analysis of microencapsulated ß-cells exposed to a biotransformed tertiary bile acid: An ex vivo study
by: Mooranian, Armin, et al.
Published: (2016)
by: Mooranian, Armin, et al.
Published: (2016)
Alginate-deoxycholic Acid Interaction and Its Impact on Pancreatic ?-Cells and Insulin Secretion and Potential Treatment of Type 1 Diabetes
by: Mooranian, Armin, et al.
Published: (2016)
by: Mooranian, Armin, et al.
Published: (2016)
Novel multicompartmental bile acid-based microcapsules for pancreatic β-cell transplantation
by: Mooranian, A., et al.
Published: (2015)
by: Mooranian, A., et al.
Published: (2015)
NOVEL MULTICOMPARTMENTAL BILE ACID-BASED MICROCAPSULES FOR PANCREATIC beta-CELL TRANSPLANTATION
by: Mooranian, A., et al.
Published: (2015)
by: Mooranian, A., et al.
Published: (2015)
The impact of allylamine-bile acid combinations on cell delivery microcapsules in diabetes
by: Mooranian, Armin, et al.
Published: (2016)
by: Mooranian, Armin, et al.
Published: (2016)
Primary Bile Acid Chenodeoxycholic Acid-Based Microcapsules to Examine ß-cell Survival and the Inflammatory Response
by: Mooranian, A., et al.
Published: (2016)
by: Mooranian, A., et al.
Published: (2016)
The biological effects of the hypolipidaemic drug probucol microcapsules fed daily for 4 weeks, to an insulin-resistant mouse model: potential hypoglycaemic and anti-inflammatory effects
by: Mooranian, Armin, et al.
Published: (2018)
by: Mooranian, Armin, et al.
Published: (2018)
The effects of Ionic Gelation- Vibrational Jet Flow technique in fabrication of microcapsules incorporating ß-cell: applications in Type-1 Diabetes
by: Mooranian, A., et al.
Published: (2017)
by: Mooranian, A., et al.
Published: (2017)
Class II phosphoinositide 3-kinase regulates exocytosis of insulin granules in pancreatic ß cells
by: Dominguez, V., et al.
Published: (2011)
by: Dominguez, V., et al.
Published: (2011)
The incorporation of water-soluble gel matrix into bile acid-based microcapsules for the delivery of viable ß-cells of the pancreas, in diabetes treatment: biocompatibility and functionality studies.
by: Mooranian, A., et al.
Published: (2015)
by: Mooranian, A., et al.
Published: (2015)
Effect of proinflammatory cytokines on lung and intestinal mucosal permeability in vitro
by: Alshehri, Abdullah Ali
Published: (2013)
by: Alshehri, Abdullah Ali
Published: (2013)
Flow vibration-doubled concentric system coupled with low ratio amine to produce bile acid-macrocapsules of ß-cells
by: Mooranian, Armin, et al.
Published: (2016)
by: Mooranian, Armin, et al.
Published: (2016)
Peroxiredoxin III protects pancreatic ß cells from apoptosis
by: Wolf, G., et al.
Published: (2010)
by: Wolf, G., et al.
Published: (2010)
Saturated and unsaturated (including arachidonic acid) non-esterified fatty acid modulation of insulin secretion from pancreatic ß-cells
by: Keane, D., et al.
Published: (2008)
by: Keane, D., et al.
Published: (2008)
GEOGENIC DUST IMPACTS CELL VIABILITY AND INFLAMMATORY CYTOKINES IN HUMAN AIRWAY EPITHELIAL CELLS
by: Clifford, H., et al.
Published: (2014)
by: Clifford, H., et al.
Published: (2014)
Prolonged L-alanine exposure induces changes in metabolism, Ca2+ handling and desensitization of insulin secretion in clonal pancreatic ß-cells
by: McClenaghan, N., et al.
Published: (2009)
by: McClenaghan, N., et al.
Published: (2009)
A synthetic curcuminoid derivative inhibits nitric oxide and proinflammatory cytokine synthesis
by: Tham, Chau Ling, et al.
Published: (2010)
by: Tham, Chau Ling, et al.
Published: (2010)
Nutrient regulation of insulin secretion and ß-cell functional integrity
by: Newsholme, Philip, et al.
Published: (2010)
by: Newsholme, Philip, et al.
Published: (2010)
Insulin and IGF-1 receptor autocrine loops are not required for Exendin-4 induced changes to pancreatic ß-cell bioenergetic parameters and metabolism in BRIN-BD11 cells
by: Rowlands, Jordan, et al.
Published: (2018)
by: Rowlands, Jordan, et al.
Published: (2018)
Advanced bile acid-based multi-compartmental microencapsulated pancreatic ß-cells integrating a polyelectrolyte-bile acid formulation, for diabetes treatment.
by: Mooranian, A., et al.
Published: (2014)
by: Mooranian, A., et al.
Published: (2014)
Long-Term Supplementation of Microencapsulated ursodeoxycholic Acid Prevents Hypertension in a Mouse Model of Insulin Resistance:
by: Al-Salami, Hani, et al.
Published: (2016)
by: Al-Salami, Hani, et al.
Published: (2016)
A synthetic hydroxypropenone inhibits nitric oxide, prostaglandin E2, and proinflammatory cytokine synthesis
by: Liew, Choi Yi, et al.
Published: (2010)
by: Liew, Choi Yi, et al.
Published: (2010)
Microparticles, microcapsules and microspheres: A review of recent developments and prospects for oral delivery of insulin
by: Wong, C., et al.
Published: (2018)
by: Wong, C., et al.
Published: (2018)
A 4D view on insulin secretory granule turnover in the ß-cell
by: Müller, A., et al.
Published: (2017)
by: Müller, A., et al.
Published: (2017)
Alanyl-glutamine improves pancreatic ß-cell function following ex vivo inflammatory challenge
by: Cruzat, Vinicius, et al.
Published: (2015)
by: Cruzat, Vinicius, et al.
Published: (2015)
Adult muscle-derived stem cells engraft and differentiate into insulin-expressing cells in pancreatic islets of diabetic mice
by: Mitutsova, Violeta, et al.
Published: (2017)
by: Mitutsova, Violeta, et al.
Published: (2017)
Novel artificial cell microencapsulation of probucol and bile acids in diabetes mellitus
by: Mooranian, Armin
Published: (2018)
by: Mooranian, Armin
Published: (2018)
Molecular Events Linking Oxidative Stress and Inflammation to Insulin Resistance and ß-Cell Dysfunction
by: Keane, Kevin, et al.
Published: (2015)
by: Keane, Kevin, et al.
Published: (2015)
Effects of pharmacological inhibition of NADPH oxidase or iNOS on pro-inflammatory cytokine, palmitic acid or H2O2-induced mouse islet or clonal pancreatic ß-cell dysfunction
by: Michalska, M., et al.
Published: (2010)
by: Michalska, M., et al.
Published: (2010)
Elevated levels of extracellular heat-shock protein 72 (eHSP72) are positively correlated with insulin resistance in vivo and cause pancreatic ß-cell dysfunction and death in vitro.
by: Krause, M., et al.
Published: (2013)
by: Krause, M., et al.
Published: (2013)
Gongronema latifolium Lowers Blood Glucose via Pancreatic Islet Cell Regeneration and Insulin Sensitization
by: Al-Hindi, Bassel, et al.
Published: (2014)
by: Al-Hindi, Bassel, et al.
Published: (2014)
Similar Items
-
Alginate-combined cholic acid increased insulin secretion of microencapsulated mouse cloned pancreatic ß cells
by: Mooranian, A., et al.
Published: (2017) -
Biological Assessments of Encapsulated Pancreatic ß-Cells: Their Potential Transplantation in Diabetes
by: Mooranian, Armin, et al.
Published: (2016) -
Designing anti-diabetic ß-cells microcapsules using polystyrenic sulfonate, polyallylamine and a tertiary bile acid: Morphology, bioenergetics and cytokine analysis.
by: Mooranian, A., et al.
Published: (2016) -
Multicompartmental, multilayered probucol microcapsules for diabetes mellitus: Formulation characterization and effects on production of insulin and inflammation in a pancreatic ß-cell line
by: Mooranian, A., et al.
Published: (2015) -
The effect of molecular weights of microencapsulating polymers on viability of mouse-cloned pancreatic ß-cells: biomaterials, osmotic forces and potential applications in diabetes treatment
by: Mooranian, A., et al.
Published: (2018)