A novel Osmium-based compound targets the mitochondria and triggers ROS-dependent apoptosis in colon carcinoma

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A novel Osmium-based compound targets the mitochondria and triggers ROS-dependent apoptosis in colon carcinoma

Engagement of the mitochondrial-death amplification pathway is an essential component in chemotherapeutic execution of cancer cells. Therefore, identification of mitochondria-targeting agents has become an attractive avenue for novel drug discovery. Here, we report the anticancer activity of a novel...

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Bibliographic Details
Main Authors:	Maillet, A., Yadav, S., Loo, Y., Sachaphibulkij, K., Pervaiz, Shazib
Format:	Journal Article
Published:	Nature Publishing Group 2013
Online Access:	http://hdl.handle.net/20.500.11937/51238

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