Synergistic Anticancer Effects Achieved by Co-Delivery of TRAIL and Paclitaxel Using Cationic Polymeric Micelles

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Synergistic Anticancer Effects Achieved by Co-Delivery of TRAIL and Paclitaxel Using Cationic Polymeric Micelles

Cationic micellar nanoparticles self-assembled from a biodegradable amphiphilic copolymer have been used to deliver human TRAIL and paclitaxel simultaneously. Polyplexes formed between paclitaxel-loaded nanoparticles and TRAIL are stable with a size of ˜180nm and a zeta potential at ˜75mV. Anticance...

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Bibliographic Details
Main Authors:	Lee, A., Wang, Y., Pervaiz, Shazib, Fan, W., Yang, Y.
Format:	Journal Article
Published:	2011
Online Access:	http://hdl.handle.net/20.500.11937/51227

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