Regulation of mitochondrial metabolism: Yet another facet in the biology of the oncoprotein Bcl-2
The Bcl-2 (Bcl is B-cell lymphocytic-leukaemia proto-oncogene) family comprises two groups of proteins with distinct functional biology in cell-fate signalling. Bcl-2 protein was the first member to be discovered and associated with drug resistance in human lymphomas. Since then a host of other prot...
| Main Authors: | Krishna, S., Low, I., Pervaiz, Shazib |
|---|---|
| Format: | Journal Article |
| Published: |
Portland Press Ltd.
2011
|
| Online Access: | http://hdl.handle.net/20.500.11937/51219 |
Similar Items
Bcl-2: A prime regulator of mitochondrial redox metabolism in cancer cells
by: Low, I., et al.
Published: (2011)
by: Low, I., et al.
Published: (2011)
Mitochondrial ROS and involvement of Bcl-2 as a mitochondrial ROS regulator
by: Chong, S., et al.
Published: (2014)
by: Chong, S., et al.
Published: (2014)
Crosstalk between p53 and mitochondrial metabolism
by: Itahana, K., et al.
Published: (2014)
by: Itahana, K., et al.
Published: (2014)
Crosstalk between Bcl-2 family and Ras family small GTPases: potential cell fate regulation?
by: Kang, J., et al.
Published: (2013)
by: Kang, J., et al.
Published: (2013)
Overexpression of Bcl-2 induces STAT-3 activation via an increase in mitochondrial superoxide.
by: Kang, J., et al.
Published: (2015)
by: Kang, J., et al.
Published: (2015)
Reactive oxygen species and oncoprotein signaling-a dangerous liaison
by: Chong, S., et al.
Published: (2018)
by: Chong, S., et al.
Published: (2018)
The anti-oxidant and pro-oxidant dichotomy of Bcl-2.
by: Yee, Y., et al.
Published: (2016)
by: Yee, Y., et al.
Published: (2016)
Ser70 phosphorylation of Bcl-2 by selective tyrosine nitration of PP2A-B56 d stabilizes its antiapoptotic activity
by: Low, I., et al.
Published: (2014)
by: Low, I., et al.
Published: (2014)
Cross talk between cellular redox state and the antiapoptotic protein Bcl-2
by: Pohl, Sebastian, et al.
Published: (2018)
by: Pohl, Sebastian, et al.
Published: (2018)
Withaferin A induces apoptosis in human melanoma cells through generation of reactive oxygen species and down-regulation of Bcl-2
by: Mayola, E., et al.
Published: (2011)
by: Mayola, E., et al.
Published: (2011)
Mitochondria: Redox metabolism and dysfunction
by: Kang, J., et al.
Published: (2012)
by: Kang, J., et al.
Published: (2012)
hTERT overexpression alleviates intracellular ROS production, improves mitochondrial function, and inhibits ROS-mediated apoptosis in cancer cells
by: Indran, I., et al.
Published: (2011)
by: Indran, I., et al.
Published: (2011)
Redox regulation of p53, redox effectors regulated by p53: A subtle balance
by: Maillet, A., et al.
Published: (2012)
by: Maillet, A., et al.
Published: (2012)
The small GTPase Rac1 is a novel binding partner of Bcl-2 and stabilizes its antiapoptotic activity
by: Velaithan, R., et al.
Published: (2011)
by: Velaithan, R., et al.
Published: (2011)
Investigating the effects of drug combinations and loss of the PRH/Hhex oncoprotein in CCA cells
by: Martin, Grace
Published: (2025)
by: Martin, Grace
Published: (2025)
Are we there Yet
by: Gray, Michael
Published: (2010)
by: Gray, Michael
Published: (2010)
Glucose metabolism is required for oxidized LDL-induced macrophage survival: Role of PI3K and Bcl-2 family proteins
by: Elsegood, Caryn, et al.
Published: (2009)
by: Elsegood, Caryn, et al.
Published: (2009)
Redox regulation of cancer cell migration and invasion
by: Tochhawng, L., et al.
Published: (2013)
by: Tochhawng, L., et al.
Published: (2013)
“I was traumatised and yet this is another trauma”: exploring resettlement challenges facing „female heads of households‟ settling in Western Australia from Africa 2001-2006
by: Mangazva, Virginia
Published: (2011)
by: Mangazva, Virginia
Published: (2011)
Repressing the activity of protein kinase CK2 releases the brakes on mitochondria-mediated apoptosis in cancer cells
by: Hanif, I., et al.
Published: (2011)
by: Hanif, I., et al.
Published: (2011)
Another Journey
by: Little, Trish
Published: (2011)
by: Little, Trish
Published: (2011)
Regulation of p53-, Bcl-2- and Caspase-dependent Signaling Pathway in Xanthorrhizol-induced Apoptosis of HepG2 Hepatoma Cells
by: Tri Handayani,, et al.
Published: (2007)
by: Tri Handayani,, et al.
Published: (2007)
Mitochondrial DNA metabolism in early development of zebrafish (Danio rerio)
by: Artuso, L., et al.
Published: (2012)
by: Artuso, L., et al.
Published: (2012)
She's not done yet
by: The Star,
Published: (2013)
by: The Star,
Published: (2013)
Common yet deadly
by: Talib, Herni
Published: (2014)
by: Talib, Herni
Published: (2014)
Boosters for teens Not yet
by: Zainal, Fatimah
Published: (2022)
by: Zainal, Fatimah
Published: (2022)
Na+/H+ exchanger 1 (NHE-1) redox-regulated gene and intracellular target for the redox control of cell death sensitivity
by: Akram, S., et al.
Published: (2011)
by: Akram, S., et al.
Published: (2011)
Role of Bcl-2 in tumour cell survival and implications for pharmacotherapy
by: Tomek, M., et al.
Published: (2012)
by: Tomek, M., et al.
Published: (2012)
Lofar Facet Calibration
by: Weeren, R., et al.
Published: (2016)
by: Weeren, R., et al.
Published: (2016)
Parsing the contributions of the BCL-2 anti-apoptotic proteins in mediating survival of nasopharyngeal carcinoma cell line HK1 using BCL-2 selective inhibitors
by: Siti Fairus Abdul Rahman,, et al.
Published: (2020)
by: Siti Fairus Abdul Rahman,, et al.
Published: (2020)
Semi-purified fraction of Clinacanthus nutans induced apoptosis in human cervical cancer, SiHa cells via up-regulation of bax and down-regulation of Bcl-2
by: Nik Aina Syazana Nik Zainuddin,, et al.
Published: (2019)
by: Nik Aina Syazana Nik Zainuddin,, et al.
Published: (2019)
Cytotoxicity of SRJ23 and its derivatives, expression and SRJ23 binding of KRas G12V oncoprotein
by: Tan, Michelle Siying
Published: (2017)
by: Tan, Michelle Siying
Published: (2017)
In silico and saturation transfer difference NMR approaches to unravel the binding mode of an andrographolide derivative to K-Ras oncoprotein
by: Shun, Ying Quah, et al.
Published: (2020)
by: Shun, Ying Quah, et al.
Published: (2020)
Another Startling Experience
by: Bradley Smith, Susan
Published: (2016)
by: Bradley Smith, Susan
Published: (2016)
One Place, and Another
by: Nazzari, Anna
Published: (2015)
by: Nazzari, Anna
Published: (2015)
Mitochondrial mistranslation modulated by metabolic stress causes cardiovascular disease and reduced lifespan
by: Richman, T.R., et al.
Published: (2021)
by: Richman, T.R., et al.
Published: (2021)
‘Latin American Modernity, and yet...’
by: Sharman, Adam
Published: (2011)
by: Sharman, Adam
Published: (2011)
Sequence and partial functional analysis of canine Bcl-2 family proteins
by: de Brot, Simone, et al.
Published: (2016)
by: de Brot, Simone, et al.
Published: (2016)
Metabolic Regulation of Insulin Secretion
by: Keane, Kevin, et al.
Published: (2014)
by: Keane, Kevin, et al.
Published: (2014)
The regulation of cellular iron metabolism
by: Chua, A., et al.
Published: (2007)
by: Chua, A., et al.
Published: (2007)
Similar Items
-
Bcl-2: A prime regulator of mitochondrial redox metabolism in cancer cells
by: Low, I., et al.
Published: (2011) -
Mitochondrial ROS and involvement of Bcl-2 as a mitochondrial ROS regulator
by: Chong, S., et al.
Published: (2014) -
Crosstalk between p53 and mitochondrial metabolism
by: Itahana, K., et al.
Published: (2014) -
Crosstalk between Bcl-2 family and Ras family small GTPases: potential cell fate regulation?
by: Kang, J., et al.
Published: (2013) -
Overexpression of Bcl-2 induces STAT-3 activation via an increase in mitochondrial superoxide.
by: Kang, J., et al.
Published: (2015)