Activation of surrogate death receptor signaling triggers peroxynitrite-dependent execution of cisplatin-resistant cancer cells

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Activation of surrogate death receptor signaling triggers peroxynitrite-dependent execution of cisplatin-resistant cancer cells

Platinum-based drugs remain as the cornerstone of cancer chemotherapy; however, development of multidrug resistance presents a therapeutic challenge. This study aims at understanding the molecular mechanisms underlying resistance to cisplatin and unraveling surrogate signaling networks that could re...

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Bibliographic Details
Main Authors:	Seah, S., Low, It Meng, Hirpara, J., Sachaphibulkij, K., Kroemer, G., Brenner, C., Pervaiz, Shazib
Format:	Journal Article
Published:	Nature Publishing Group 2015
Online Access:	http://hdl.handle.net/20.500.11937/51036

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