Withaferin A induces apoptosis in human melanoma cells through generation of reactive oxygen species and down-regulation of Bcl-2

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Withaferin A induces apoptosis in human melanoma cells through generation of reactive oxygen species and down-regulation of Bcl-2

A high resistance and heterogeneous response to conventional anti-cancer chemotherapies characterize malignant cutaneous melanoma, the most aggressive and deadly form of skin cancer. Withaferin A (WFA), a withanolide derived from the medicinal plant Withania somnifera, has been reported for its anti...

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Bibliographic Details
Main Authors:	Mayola, E., Gallerne, C., Esposti, D., Martel, C., Pervaiz, Shazib, Larue, L., Debuire, B., Lemoine, A., Brenner, C., Lemaire, C.
Format:	Journal Article
Published:	Springer 2011
Online Access:	http://hdl.handle.net/20.500.11937/50989

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