Analysis of nocturnal actigraphic sleep measures in patients with COPD and their association with daytime physical activity

Background: Sleep disturbances are common in patients with chronic obstructive pulmonary disease (COPD) with a considerable negative impact on their quality of life. However, factors associated with measures of sleep in daily life have not been investigated before nor has the association between sle...

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Main Authors: Spina, G., Spruit, M., Alison, J., Benzo, R., Calverley, P., Clarenbach, C., Costello, R., Donaire-Gonzalez, D., Dürr, S., Garcia-Aymerich, J., van Gestel, A., Gramm, M., Hernandes, N., Hill, Kylie, Hopkinson, N., Jarreta, D., Kohler, M., Kirsten, A., Leuppi, J., Magnussen, H., Maltais, F., Man, W., McKeough, Z., Mesquita, R., Miedinger, D., Pitta, F., Singh, S., Smeenk, F., Tal-Singer, R., Vagaggini, B., Waschki, B., Watz, H., Wouters, E., Zogg, S., den Brinker, A.
Format: Journal Article
Published: BMJ Group 2017
Online Access:http://hdl.handle.net/20.500.11937/50972
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author Spina, G.
Spruit, M.
Alison, J.
Benzo, R.
Calverley, P.
Clarenbach, C.
Costello, R.
Donaire-Gonzalez, D.
Dürr, S.
Garcia-Aymerich, J.
van Gestel, A.
Gramm, M.
Hernandes, N.
Hill, Kylie
Hopkinson, N.
Jarreta, D.
Kohler, M.
Kirsten, A.
Leuppi, J.
Magnussen, H.
Maltais, F.
Man, W.
McKeough, Z.
Mesquita, R.
Miedinger, D.
Pitta, F.
Singh, S.
Smeenk, F.
Tal-Singer, R.
Vagaggini, B.
Waschki, B.
Watz, H.
Wouters, E.
Zogg, S.
den Brinker, A.
author_facet Spina, G.
Spruit, M.
Alison, J.
Benzo, R.
Calverley, P.
Clarenbach, C.
Costello, R.
Donaire-Gonzalez, D.
Dürr, S.
Garcia-Aymerich, J.
van Gestel, A.
Gramm, M.
Hernandes, N.
Hill, Kylie
Hopkinson, N.
Jarreta, D.
Kohler, M.
Kirsten, A.
Leuppi, J.
Magnussen, H.
Maltais, F.
Man, W.
McKeough, Z.
Mesquita, R.
Miedinger, D.
Pitta, F.
Singh, S.
Smeenk, F.
Tal-Singer, R.
Vagaggini, B.
Waschki, B.
Watz, H.
Wouters, E.
Zogg, S.
den Brinker, A.
author_sort Spina, G.
building Curtin Institutional Repository
collection Online Access
description Background: Sleep disturbances are common in patients with chronic obstructive pulmonary disease (COPD) with a considerable negative impact on their quality of life. However, factors associated with measures of sleep in daily life have not been investigated before nor has the association between sleep and the ability to engage in physical activity on a day-to-day basis been studied. Aims: To provide insight into the relationship between actigraphic sleep measures and disease severity, exertional dyspnoea, gender and parts of the week; and to investigate the association between sleep measures and next day physical activity. Methods: Data were analysed from 932 patients with COPD (66% male, 66.4±8.3 years, FEV1% predicted=50.8±20.5). Participants had sleep and physical activity continuously monitored using a multisensor activity monitor for a median of 6 days. Linear mixed effects models were applied to investigate the factors associated with sleep impairment and the association between nocturnal sleep and patients' subsequent daytime physical activity. Results: Actigraphic estimates of sleep impairment were greater in patients with worse airflow limitation and worse exertional dyspnoea. Patients with better sleep measures (ie, non-fragmented sleep, sleeping bouts ≥225 min, sleep efficiency ≥91% and time spent awake after sleep onset <57 min) spent significantly more time in light (<0.01) and moderate-to-vigorous physical activity (<0.01). Conclusions: There is a relationship between measures of sleep in patients with COPD and the amount of activity they undertake during the waking day. Identifying groups with specific sleep characteristics may be useful information when designing physical activity-enhancing interventions.
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spelling curtin-20.500.11937-509722017-09-13T16:09:42Z Analysis of nocturnal actigraphic sleep measures in patients with COPD and their association with daytime physical activity Spina, G. Spruit, M. Alison, J. Benzo, R. Calverley, P. Clarenbach, C. Costello, R. Donaire-Gonzalez, D. Dürr, S. Garcia-Aymerich, J. van Gestel, A. Gramm, M. Hernandes, N. Hill, Kylie Hopkinson, N. Jarreta, D. Kohler, M. Kirsten, A. Leuppi, J. Magnussen, H. Maltais, F. Man, W. McKeough, Z. Mesquita, R. Miedinger, D. Pitta, F. Singh, S. Smeenk, F. Tal-Singer, R. Vagaggini, B. Waschki, B. Watz, H. Wouters, E. Zogg, S. den Brinker, A. Background: Sleep disturbances are common in patients with chronic obstructive pulmonary disease (COPD) with a considerable negative impact on their quality of life. However, factors associated with measures of sleep in daily life have not been investigated before nor has the association between sleep and the ability to engage in physical activity on a day-to-day basis been studied. Aims: To provide insight into the relationship between actigraphic sleep measures and disease severity, exertional dyspnoea, gender and parts of the week; and to investigate the association between sleep measures and next day physical activity. Methods: Data were analysed from 932 patients with COPD (66% male, 66.4±8.3 years, FEV1% predicted=50.8±20.5). Participants had sleep and physical activity continuously monitored using a multisensor activity monitor for a median of 6 days. Linear mixed effects models were applied to investigate the factors associated with sleep impairment and the association between nocturnal sleep and patients' subsequent daytime physical activity. Results: Actigraphic estimates of sleep impairment were greater in patients with worse airflow limitation and worse exertional dyspnoea. Patients with better sleep measures (ie, non-fragmented sleep, sleeping bouts ≥225 min, sleep efficiency ≥91% and time spent awake after sleep onset <57 min) spent significantly more time in light (<0.01) and moderate-to-vigorous physical activity (<0.01). Conclusions: There is a relationship between measures of sleep in patients with COPD and the amount of activity they undertake during the waking day. Identifying groups with specific sleep characteristics may be useful information when designing physical activity-enhancing interventions. 2017 Journal Article http://hdl.handle.net/20.500.11937/50972 10.1136/thoraxjnl-2016-208900 BMJ Group fulltext
spellingShingle Spina, G.
Spruit, M.
Alison, J.
Benzo, R.
Calverley, P.
Clarenbach, C.
Costello, R.
Donaire-Gonzalez, D.
Dürr, S.
Garcia-Aymerich, J.
van Gestel, A.
Gramm, M.
Hernandes, N.
Hill, Kylie
Hopkinson, N.
Jarreta, D.
Kohler, M.
Kirsten, A.
Leuppi, J.
Magnussen, H.
Maltais, F.
Man, W.
McKeough, Z.
Mesquita, R.
Miedinger, D.
Pitta, F.
Singh, S.
Smeenk, F.
Tal-Singer, R.
Vagaggini, B.
Waschki, B.
Watz, H.
Wouters, E.
Zogg, S.
den Brinker, A.
Analysis of nocturnal actigraphic sleep measures in patients with COPD and their association with daytime physical activity
title Analysis of nocturnal actigraphic sleep measures in patients with COPD and their association with daytime physical activity
title_full Analysis of nocturnal actigraphic sleep measures in patients with COPD and their association with daytime physical activity
title_fullStr Analysis of nocturnal actigraphic sleep measures in patients with COPD and their association with daytime physical activity
title_full_unstemmed Analysis of nocturnal actigraphic sleep measures in patients with COPD and their association with daytime physical activity
title_short Analysis of nocturnal actigraphic sleep measures in patients with COPD and their association with daytime physical activity
title_sort analysis of nocturnal actigraphic sleep measures in patients with copd and their association with daytime physical activity
url http://hdl.handle.net/20.500.11937/50972