Diagnostic Performance of Mandibular Bone Density Measurements in Assessing Osteoporotic Status
PURPOSE: The study evaluated the diagnostic performance of computed tomography (CT) bone density measurements (in Hounsfield units [HU]) in assessing the osteoporotic status of edentulous subjects (21 men, 40 women) scheduled to receive mandibular implant-supported overdentures. MATERIALS AND METHOD...
| Main Authors: | , , , |
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| Format: | Journal Article |
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Quintessence Publishing
2014
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| Online Access: | http://hdl.handle.net/20.500.11937/50887 |
| _version_ | 1848758560251445248 |
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| author | Chai, J. Chau, Anson Chu, F. Chow, T. |
| author_facet | Chai, J. Chau, Anson Chu, F. Chow, T. |
| author_sort | Chai, J. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | PURPOSE: The study evaluated the diagnostic performance of computed tomography (CT) bone density measurements (in Hounsfield units [HU]) in assessing the osteoporotic status of edentulous subjects (21 men, 40 women) scheduled to receive mandibular implant-supported overdentures. MATERIALS AND METHODS: Density (in HU) of 61 left and 61 right mandibular canine sites was measured. Each subject was also subject to body bone mineral density measurements (dual-energy x-ray absorptiometry). Bone density T-score values of total hip, femoral neck, spine (L1 to L4), and total body were assessed. Pearson correlations were conducted between HU of each mandibular bone site and the subject's T-score values. Sensitivity/specificity and receiver operating characteristic curve analyses were used to assess the diagnostic performance of HU in detecting subjects who were, based on each of the four T-scores: (1) "not osteonormal", ie, with a T-score at or below -1.0; or (2) osteoporotic, ie, with a T-score at or below -2.5. RESULTS: HU measurements of mandibular bone sites were found to have modest but significant correlations with each bone density T-score value (total hip, femoral neck, spine, total body). CT mandibular site HU measurement has diagnostic value in detecting a "not osteonormal" condition when total hip, spine, or total body T-scores were used, but not when femoral neck T-score was used. CONCLUSIONS: Based on the limited sample size, optimal HU cutoff values of ~530, ~600, and ~640 HU for total hip, spine, or total body T-scores, respectively, were proposed. CT mandibular site HU measurement had diagnostic value in detecting osteoporosis when spine T-score was used but not when total hip, femoral neck, and total body T-scores were used. An optimal HU cutoff value of ~460 HU for spine T-score was proposed. |
| first_indexed | 2025-11-14T09:45:56Z |
| format | Journal Article |
| id | curtin-20.500.11937-50887 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T09:45:56Z |
| publishDate | 2014 |
| publisher | Quintessence Publishing |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-508872017-03-17T08:29:01Z Diagnostic Performance of Mandibular Bone Density Measurements in Assessing Osteoporotic Status Chai, J. Chau, Anson Chu, F. Chow, T. PURPOSE: The study evaluated the diagnostic performance of computed tomography (CT) bone density measurements (in Hounsfield units [HU]) in assessing the osteoporotic status of edentulous subjects (21 men, 40 women) scheduled to receive mandibular implant-supported overdentures. MATERIALS AND METHODS: Density (in HU) of 61 left and 61 right mandibular canine sites was measured. Each subject was also subject to body bone mineral density measurements (dual-energy x-ray absorptiometry). Bone density T-score values of total hip, femoral neck, spine (L1 to L4), and total body were assessed. Pearson correlations were conducted between HU of each mandibular bone site and the subject's T-score values. Sensitivity/specificity and receiver operating characteristic curve analyses were used to assess the diagnostic performance of HU in detecting subjects who were, based on each of the four T-scores: (1) "not osteonormal", ie, with a T-score at or below -1.0; or (2) osteoporotic, ie, with a T-score at or below -2.5. RESULTS: HU measurements of mandibular bone sites were found to have modest but significant correlations with each bone density T-score value (total hip, femoral neck, spine, total body). CT mandibular site HU measurement has diagnostic value in detecting a "not osteonormal" condition when total hip, spine, or total body T-scores were used, but not when femoral neck T-score was used. CONCLUSIONS: Based on the limited sample size, optimal HU cutoff values of ~530, ~600, and ~640 HU for total hip, spine, or total body T-scores, respectively, were proposed. CT mandibular site HU measurement had diagnostic value in detecting osteoporosis when spine T-score was used but not when total hip, femoral neck, and total body T-scores were used. An optimal HU cutoff value of ~460 HU for spine T-score was proposed. 2014 Journal Article http://hdl.handle.net/20.500.11937/50887 Quintessence Publishing restricted |
| spellingShingle | Chai, J. Chau, Anson Chu, F. Chow, T. Diagnostic Performance of Mandibular Bone Density Measurements in Assessing Osteoporotic Status |
| title | Diagnostic Performance of Mandibular Bone Density Measurements in Assessing Osteoporotic Status |
| title_full | Diagnostic Performance of Mandibular Bone Density Measurements in Assessing Osteoporotic Status |
| title_fullStr | Diagnostic Performance of Mandibular Bone Density Measurements in Assessing Osteoporotic Status |
| title_full_unstemmed | Diagnostic Performance of Mandibular Bone Density Measurements in Assessing Osteoporotic Status |
| title_short | Diagnostic Performance of Mandibular Bone Density Measurements in Assessing Osteoporotic Status |
| title_sort | diagnostic performance of mandibular bone density measurements in assessing osteoporotic status |
| url | http://hdl.handle.net/20.500.11937/50887 |