The three Rs along the TRAIL: Resistance, re-sensitization and reactive oxygen species (ROS)
Ligation of the Tumour necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) death receptors has been associated with cancer specific apoptotic execution in a number of model systems. This has generated tremendous interest in the use of TRAIL as a potential therapeutic modality. However, r...
| Main Authors: | Mellier, G., Pervaiz, Shazib |
|---|---|
| Format: | Journal Article |
| Published: |
2012
|
| Online Access: | http://hdl.handle.net/20.500.11937/50874 |
Similar Items
Reactive oxygen species (ROS) and sensitization to TRAIL-induced apoptosis, in Bayesian network modelling of HeLa cell response to LY303511
by: Tucker-Kellogg, L., et al.
Published: (2012)
by: Tucker-Kellogg, L., et al.
Published: (2012)
Reactive Oxygen Species (ROS) in cancer and cancer stem cells
by: Hikmah, Febrial, et al.
Published: (2021)
by: Hikmah, Febrial, et al.
Published: (2021)
Small molecule sensitization to TRAIL is mediated via nuclear localization, phosphorylation and inhibition of chaperone activity of Hsp27
by: Mellier, G., et al.
Published: (2013)
by: Mellier, G., et al.
Published: (2013)
Reactive oxygen species and oncoprotein signaling-a dangerous liaison
by: Chong, S., et al.
Published: (2018)
by: Chong, S., et al.
Published: (2018)
Assessment of reactive oxygen species (ROS) status in chronic cerebral hypoperfusion-induced neurodegeneration
by: Abdul Majeed, Saif Saad, et al.
Published: (2011)
by: Abdul Majeed, Saif Saad, et al.
Published: (2011)
Mitochondrial ROS and involvement of Bcl-2 as a mitochondrial ROS regulator
by: Chong, S., et al.
Published: (2014)
by: Chong, S., et al.
Published: (2014)
Computational modelling of LY303511 and TRAIL-induced apoptosis suggests dynamic regulation of cFLIP
by: Shi, Y., et al.
Published: (2013)
by: Shi, Y., et al.
Published: (2013)
hTERT overexpression alleviates intracellular ROS production, improves mitochondrial function, and inhibits ROS-mediated apoptosis in cancer cells
by: Indran, I., et al.
Published: (2011)
by: Indran, I., et al.
Published: (2011)
ROS, autophagy, mitochondria and cancer: Ras, the hidden master?
by: Bellot, G., et al.
Published: (2013)
by: Bellot, G., et al.
Published: (2013)
Reactive oxygen species (ROS) mediated enhanced anti-candidal activity of ZnS-ZnO nanocomposites with low inhibitory concentrations
by: Suyana, P., et al.
Published: (2015)
by: Suyana, P., et al.
Published: (2015)
Gelsolin-Cu/ZnSOD interaction alters intracellular reactive oxygen species levels to promote cancer cell invasion.
by: Tochhawng, L., et al.
Published: (2016)
by: Tochhawng, L., et al.
Published: (2016)
Withaferin A induces apoptosis in human melanoma cells through generation of reactive oxygen species and down-regulation of Bcl-2
by: Mayola, E., et al.
Published: (2011)
by: Mayola, E., et al.
Published: (2011)
Characterization of the reactive oxygen species and reactive nitrogen species defense system in berangan banana / Fung Shi Ming
by: Fung , Shi Ming
Published: (2022)
by: Fung , Shi Ming
Published: (2022)
A distinct reactive oxygen species profile confers chemoresistance in glioma-propagating cells and associates with patient survival outcome
by: Koh, L., et al.
Published: (2013)
by: Koh, L., et al.
Published: (2013)
The role of reactive oxygen species in pressure-dependent myogenic tone
by: Satirah Zainalabidin,, et al.
Published: (2012)
by: Satirah Zainalabidin,, et al.
Published: (2012)
Diet, Obesity, and Reactive Oxygen Species – Implications for Diabetes and Aging
by: Newsholme, Philip, et al.
Published: (2014)
by: Newsholme, Philip, et al.
Published: (2014)
A novel Osmium-based compound targets the mitochondria and triggers ROS-dependent apoptosis in colon carcinoma
by: Maillet, A., et al.
Published: (2013)
by: Maillet, A., et al.
Published: (2013)
Synergistic Anticancer Effects Achieved by Co-Delivery of TRAIL and Paclitaxel Using Cationic Polymeric Micelles
by: Lee, A., et al.
Published: (2011)
by: Lee, A., et al.
Published: (2011)
Reactive oxygen species and aldehyde dehydrogenase activity in Hodgkin lymphoma cells
by: Ikeda, Jun-ichiro, et al.
Published: (2012)
by: Ikeda, Jun-ichiro, et al.
Published: (2012)
Preliminary study on overproduction of reactive oxygen species by neutrophils in diabetes mellitus
by: Ridzuan, Noridzzaida, et al.
Published: (2016)
by: Ridzuan, Noridzzaida, et al.
Published: (2016)
Dengue Virus-Induced Reactive Oxygen Species Production in Rat Microglial Cells
by: Lattapon, Suwanprinya, et al.
Published: (2017)
by: Lattapon, Suwanprinya, et al.
Published: (2017)
Synergistic anticancer effects via co-delivery of TNF-related apoptosis-inducing ligand (TRAIL) and doxorubicin using micellar polymer nanoparticles
by: Lee, A., et al.
Published: (2012)
by: Lee, A., et al.
Published: (2012)
Macrofungi diversity in secondary forest of three forest trails
by: Pit, Norshipha
Published: (2018)
by: Pit, Norshipha
Published: (2018)
Reactive oxygen species, mitochondria, and endothelial cell death during in vitro simulated dives
by: Wang, Q., et al.
Published: (2015)
by: Wang, Q., et al.
Published: (2015)
Porphyrinic-nanoplatforms: controlled intracellular generation of reactive oxygen species in human mesenchymal stem cells
by: Lavado, Andrea Sofia Caetano das Neves
Published: (2014)
by: Lavado, Andrea Sofia Caetano das Neves
Published: (2014)
Effect of food colorants supplementation on reactive oxygen species, antioxidant vitamins level and DNA damage
by: Shakoor, Sadaf, et al.
Published: (2021)
by: Shakoor, Sadaf, et al.
Published: (2021)
Reactive Oxygen Species Play a Role in the Infection of the Necrotrophic Fungi, Rhizoctonia solani in Wheat
by: Foley, R., et al.
Published: (2016)
by: Foley, R., et al.
Published: (2016)
Mechanisms of PEDF-mediated protection against reactive oxygen species damage in diabetic retinopathy and neuropathy
by: Elahy, M., et al.
Published: (2014)
by: Elahy, M., et al.
Published: (2014)
Effect of food colorants supplementation on reactive oxygen species, antioxidant vitamins level and DNA damage
by: Shakoor, Sadaf, et al.
Published: (2021)
by: Shakoor, Sadaf, et al.
Published: (2021)
Diversity and distribution of fern species in selected trail in Kuantan Pahang
by: Sahrom, Izyan Nazihah, et al.
Published: (2018)
by: Sahrom, Izyan Nazihah, et al.
Published: (2018)
KIF1Bß increases ROS to mediate apoptosis and reinforces its protein expression through O2− in a positive feedback mechanism in neuroblastoma
by: Angelina, C., et al.
Published: (2017)
by: Angelina, C., et al.
Published: (2017)
Synergistic anti-cancer effects via co-delivery of TNF-related apoptosis-inducing ligand (TRAIL/Apo2L) and doxorubicin using micellar nanoparticles
by: Lee, A., et al.
Published: (2011)
by: Lee, A., et al.
Published: (2011)
Na+/H+ exchanger 1 (NHE-1) redox-regulated gene and intracellular target for the redox control of cell death sensitivity
by: Akram, S., et al.
Published: (2011)
by: Akram, S., et al.
Published: (2011)
Triphenyltin(IV) benzoates with diazenyl/imino scaffold exhibiting remarkable apoptosis mediated by reactive oxygen species
by: Basu Baul, Tushar S., et al.
Published: (2017)
by: Basu Baul, Tushar S., et al.
Published: (2017)
Exploiting the reactive oxygen species imbalance in high-risk paediatric acute lymphoblastic leukaemia through auranofin.
by: Karsa, Mawar, et al.
Published: (2021)
by: Karsa, Mawar, et al.
Published: (2021)
Role of Focal Adhesion Tyrosine Kinases in GPVI-Dependent Platelet Activation and Reactive Oxygen Species Formation
by: Carrim, N., et al.
Published: (2014)
by: Carrim, N., et al.
Published: (2014)
Synthetic Lethality of a Novel Small Molecule Against Mutant KRAS-Expressing Cancer Cells Involves AKT-Dependent ROS Production
by: Iskandar, K., et al.
Published: (2016)
by: Iskandar, K., et al.
Published: (2016)
Evaluation of recreation-use impacts in relation to physical factors along Gunung Datok Trail, Negeri Sembilan, Malaysia
by: Jumaat, Noor Jalilah
Published: (2013)
by: Jumaat, Noor Jalilah
Published: (2013)
Renoprotective and antihypertensive mechanism of action of Clinacanthus nutans bioactive polysaccharides by suppression of reactive oxygen species/ nuclear factor/ matrix metalloproteinase (ROS/NF-ΚB/MMP-9) and upregulation of endothelial nitric oxide synthase/nitric oxide (eNOS/NO) pathways
by: Chia, Tan Yong, et al.
Published: (2025)
by: Chia, Tan Yong, et al.
Published: (2025)
Assessment of reactive oxygen species status and neuroprotection by vitamin e in chronic cerebral ypoperfusion-induced neurodegeneration in rats
by: Sayeed, Sayyada, et al.
Published: (2015)
by: Sayeed, Sayyada, et al.
Published: (2015)
Similar Items
-
Reactive oxygen species (ROS) and sensitization to TRAIL-induced apoptosis, in Bayesian network modelling of HeLa cell response to LY303511
by: Tucker-Kellogg, L., et al.
Published: (2012) -
Reactive Oxygen Species (ROS) in cancer and cancer stem cells
by: Hikmah, Febrial, et al.
Published: (2021) -
Small molecule sensitization to TRAIL is mediated via nuclear localization, phosphorylation and inhibition of chaperone activity of Hsp27
by: Mellier, G., et al.
Published: (2013) -
Reactive oxygen species and oncoprotein signaling-a dangerous liaison
by: Chong, S., et al.
Published: (2018) -
Assessment of reactive oxygen species (ROS) status in chronic cerebral hypoperfusion-induced neurodegeneration
by: Abdul Majeed, Saif Saad, et al.
Published: (2011)