Ascochlorin, an isoprenoid antibiotic inhibits growth and invasion of hepatocellular carcinoma by targeting STAT3 signaling cascade through the induction of PIAS3

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Ascochlorin, an isoprenoid antibiotic inhibits growth and invasion of hepatocellular carcinoma by targeting STAT3 signaling cascade through the induction of PIAS3

Deregulated activation of oncogenic transcription factors such as signal transducer and activator of transcription 3 (STAT3) plays a pivotal role in proliferation and survival of hepatocellular carcinoma (HCC). Thus, agents which can inhibit STAT3 activation may have an enormous potential for treatm...

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Bibliographic Details
Main Authors:	Dai, X., Ahn, K., Kim, C., Siveen, K., Ong, T., Shanmugam, M., Li, F., Shi, J., Kumar, Alan Prem, Wang, L., Goh, B., Magae, J., Hui, K., Sethi, G.
Format:	Journal Article
Published:	Elsevier 2015
Online Access:	http://hdl.handle.net/20.500.11937/50847

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