NDMA formation by chloramination of ranitidine: Kinetics and mechanism

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NDMA formation by chloramination of ranitidine: Kinetics and mechanism

The kinetics of decomposition of the pharmaceutical ranitidine (a major precursor of NDMA) during chloramination was investigated and some decomposition byproducts were identified by using high performance liquid chromatography coupled with mass spectrometry (HPLC-MS). The reaction between monochlor...

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Bibliographic Details
Main Authors:	Roux, J., Gallard, H., Croué, Jean-Philippe, Papot, S., Deborde, M.
Format:	Journal Article
Published:	American Chemical Society 2012
Online Access:	http://hdl.handle.net/20.500.11937/50189

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