Contribution of screening and survival differences to racial disparities in colorectal cancer rates
Background: Considerable disparities exist in colorectal cancer (CRC) incidence and mortality rates between blacks and whites in the United States. We estimated how much of these disparities could be explained by differences in CRC screening and stage-specific relative CRC survival. Methods: We used...
| Main Authors: | , , , , , |
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| Format: | Journal Article |
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American Association for Cancer Research Inc
2012
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| Online Access: | http://hdl.handle.net/20.500.11937/50079 |
| _version_ | 1848758388908883968 |
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| author | Lansdorp_Vogelaar, Iris Kuntz, K. Knudsen, A. Van Ballegooijen, M. Zauber, A. Jemal, A. |
| author_facet | Lansdorp_Vogelaar, Iris Kuntz, K. Knudsen, A. Van Ballegooijen, M. Zauber, A. Jemal, A. |
| author_sort | Lansdorp_Vogelaar, Iris |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Background: Considerable disparities exist in colorectal cancer (CRC) incidence and mortality rates between blacks and whites in the United States. We estimated how much of these disparities could be explained by differences in CRC screening and stage-specific relative CRC survival. Methods: We used the MISCAN-Colon microsimulation model to estimate CRC incidence and mortality rates in blacks, aged 50 years and older, from 1975 to 2007 assuming they had: (i) the same trends in screening rates as whites instead of observed screening rates (incidence and mortality); (ii) the same trends in stage-specific relative CRC survival rates as whites instead of observed (mortality only); and (iii) a combination of both. The racial disparities inCRC incidence and mortality rates attributable to differences in screening and/or stage-specific relative CRC survival were then calculated by comparing rates from these scenarios to the observed black rates. Results: Differences in screening accounted for 42% of disparity in CRC incidence and 19% of disparity in CRC mortality between blacks and whites. Thirty-six percent of the disparity in CRC mortality could be attributed to differences in stage-specific relative CRC survival. Together screening and survival explained a little more than 50% of the disparity in CRC mortality between blacks and whites. Conclusion: Differences in screening and relative CRC survival are responsible for a considerable proportion of the observed disparities in CRC incidence and mortality rates between blacks and whites. Impact: Enabling blacks to achieve equal access to care as whites could substantially reduce the racial disparities in CRC burden. |
| first_indexed | 2025-11-14T09:43:12Z |
| format | Journal Article |
| id | curtin-20.500.11937-50079 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T09:43:12Z |
| publishDate | 2012 |
| publisher | American Association for Cancer Research Inc |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-500792023-02-22T06:24:18Z Contribution of screening and survival differences to racial disparities in colorectal cancer rates Lansdorp_Vogelaar, Iris Kuntz, K. Knudsen, A. Van Ballegooijen, M. Zauber, A. Jemal, A. Background: Considerable disparities exist in colorectal cancer (CRC) incidence and mortality rates between blacks and whites in the United States. We estimated how much of these disparities could be explained by differences in CRC screening and stage-specific relative CRC survival. Methods: We used the MISCAN-Colon microsimulation model to estimate CRC incidence and mortality rates in blacks, aged 50 years and older, from 1975 to 2007 assuming they had: (i) the same trends in screening rates as whites instead of observed screening rates (incidence and mortality); (ii) the same trends in stage-specific relative CRC survival rates as whites instead of observed (mortality only); and (iii) a combination of both. The racial disparities inCRC incidence and mortality rates attributable to differences in screening and/or stage-specific relative CRC survival were then calculated by comparing rates from these scenarios to the observed black rates. Results: Differences in screening accounted for 42% of disparity in CRC incidence and 19% of disparity in CRC mortality between blacks and whites. Thirty-six percent of the disparity in CRC mortality could be attributed to differences in stage-specific relative CRC survival. Together screening and survival explained a little more than 50% of the disparity in CRC mortality between blacks and whites. Conclusion: Differences in screening and relative CRC survival are responsible for a considerable proportion of the observed disparities in CRC incidence and mortality rates between blacks and whites. Impact: Enabling blacks to achieve equal access to care as whites could substantially reduce the racial disparities in CRC burden. 2012 Journal Article http://hdl.handle.net/20.500.11937/50079 10.1158/1055-9965.EPI-12-0023 American Association for Cancer Research Inc unknown |
| spellingShingle | Lansdorp_Vogelaar, Iris Kuntz, K. Knudsen, A. Van Ballegooijen, M. Zauber, A. Jemal, A. Contribution of screening and survival differences to racial disparities in colorectal cancer rates |
| title | Contribution of screening and survival differences to racial disparities in colorectal cancer rates |
| title_full | Contribution of screening and survival differences to racial disparities in colorectal cancer rates |
| title_fullStr | Contribution of screening and survival differences to racial disparities in colorectal cancer rates |
| title_full_unstemmed | Contribution of screening and survival differences to racial disparities in colorectal cancer rates |
| title_short | Contribution of screening and survival differences to racial disparities in colorectal cancer rates |
| title_sort | contribution of screening and survival differences to racial disparities in colorectal cancer rates |
| url | http://hdl.handle.net/20.500.11937/50079 |