γ-Tocotrienol is a novel inhibitor of constitutive and inducible STAT3 signalling pathway in human hepatocellular carcinoma: Potential role as an antiproliferative, pro-apoptotic and chemosensitizing agent

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γ-Tocotrienol is a novel inhibitor of constitutive and inducible STAT3 signalling pathway in human hepatocellular carcinoma: Potential role as an antiproliferative, pro-apoptotic and chemosensitizing agent

BACKGROUND AND PURPOSE Activation of signal transducer and activator of transcription 3 (STAT3) play a critical role in the survival, proliferation, angiogenesis and chemoresistance of tumour cells. Thus, agents that suppress STAT3 phosphorylation have potential as cancer therapies. In the present s...

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Bibliographic Details
Main Authors:	Rajendran, P., Li, F., Manu, K., Shanmugam, M., Loo, S., Kumar, Alan Prem, Sethi, G.
Format:	Journal Article
Published:	John Wiley & Sons 2011
Online Access:	http://hdl.handle.net/20.500.11937/50076

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