Optimal colorectal cancer screening in states' low-income, uninsured populations - The case of South Carolina
© Health Research and Educational Trust.Objective To determine whether, given a limited budget, a state's low-income uninsured population would have greater benefit from a colorectal cancer (CRC) screening program using colonoscopy or fecal immunochemical testing (FIT). Data Sources/Study Setti...
| Main Authors: | , , , , , , , , , |
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| Format: | Journal Article |
| Published: |
Blackwell Publishing Inc.
2015
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| Online Access: | http://hdl.handle.net/20.500.11937/49791 |
| _version_ | 1848758315212865536 |
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| author | Van Der Steen, A. Knudsen, A. Van Hees, F. Walter, G. Berger, F. Daguise, V. Kuntz, K. Zauber, A. Van Ballegooijen, M. Lansdorp_Vogelaar, Iris |
| author_facet | Van Der Steen, A. Knudsen, A. Van Hees, F. Walter, G. Berger, F. Daguise, V. Kuntz, K. Zauber, A. Van Ballegooijen, M. Lansdorp_Vogelaar, Iris |
| author_sort | Van Der Steen, A. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | © Health Research and Educational Trust.Objective To determine whether, given a limited budget, a state's low-income uninsured population would have greater benefit from a colorectal cancer (CRC) screening program using colonoscopy or fecal immunochemical testing (FIT). Data Sources/Study Setting South Carolina's low-income, uninsured population. Study Design Comparative effectiveness analysis using microsimulation modeling to estimate the number of individuals screened, CRC cases prevented, CRC deaths prevented, and life-years gained from a screening program using colonoscopy versus a program using annual FIT in South Carolina's low-income, uninsured population. This analysis assumed an annual budget of $1 million and a budget availability of 2 years as a base case. Principal Findings The annual FIT screening program resulted in nearly eight times more individuals being screened, and more important, approximately four times as many CRC deaths prevented and life-years gained than the colonoscopy screening program. Our results were robust for assumptions concerning economic perspective and the target population, and they may therefore be generalized to other states and populations. Conclusions A FIT screening program will prevent more CRC deaths than a colonoscopy-based program when a state's budget for CRC screening supports screening of only a fraction of the target population. |
| first_indexed | 2025-11-14T09:42:02Z |
| format | Journal Article |
| id | curtin-20.500.11937-49791 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T09:42:02Z |
| publishDate | 2015 |
| publisher | Blackwell Publishing Inc. |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-497912018-03-29T09:07:46Z Optimal colorectal cancer screening in states' low-income, uninsured populations - The case of South Carolina Van Der Steen, A. Knudsen, A. Van Hees, F. Walter, G. Berger, F. Daguise, V. Kuntz, K. Zauber, A. Van Ballegooijen, M. Lansdorp_Vogelaar, Iris © Health Research and Educational Trust.Objective To determine whether, given a limited budget, a state's low-income uninsured population would have greater benefit from a colorectal cancer (CRC) screening program using colonoscopy or fecal immunochemical testing (FIT). Data Sources/Study Setting South Carolina's low-income, uninsured population. Study Design Comparative effectiveness analysis using microsimulation modeling to estimate the number of individuals screened, CRC cases prevented, CRC deaths prevented, and life-years gained from a screening program using colonoscopy versus a program using annual FIT in South Carolina's low-income, uninsured population. This analysis assumed an annual budget of $1 million and a budget availability of 2 years as a base case. Principal Findings The annual FIT screening program resulted in nearly eight times more individuals being screened, and more important, approximately four times as many CRC deaths prevented and life-years gained than the colonoscopy screening program. Our results were robust for assumptions concerning economic perspective and the target population, and they may therefore be generalized to other states and populations. Conclusions A FIT screening program will prevent more CRC deaths than a colonoscopy-based program when a state's budget for CRC screening supports screening of only a fraction of the target population. 2015 Journal Article http://hdl.handle.net/20.500.11937/49791 10.1111/1475-6773.12246 Blackwell Publishing Inc. restricted |
| spellingShingle | Van Der Steen, A. Knudsen, A. Van Hees, F. Walter, G. Berger, F. Daguise, V. Kuntz, K. Zauber, A. Van Ballegooijen, M. Lansdorp_Vogelaar, Iris Optimal colorectal cancer screening in states' low-income, uninsured populations - The case of South Carolina |
| title | Optimal colorectal cancer screening in states' low-income, uninsured populations - The case of South Carolina |
| title_full | Optimal colorectal cancer screening in states' low-income, uninsured populations - The case of South Carolina |
| title_fullStr | Optimal colorectal cancer screening in states' low-income, uninsured populations - The case of South Carolina |
| title_full_unstemmed | Optimal colorectal cancer screening in states' low-income, uninsured populations - The case of South Carolina |
| title_short | Optimal colorectal cancer screening in states' low-income, uninsured populations - The case of South Carolina |
| title_sort | optimal colorectal cancer screening in states' low-income, uninsured populations - the case of south carolina |
| url | http://hdl.handle.net/20.500.11937/49791 |