Development of Affordable Effective Vaccines against Whooping Cough for the Developing World

The rate of mortality in children associated with serious infectious diseases is significantly higher in the developing world and in socioeconomically disadvantaged populations in developed industrialized countries. The reasons underpinning the higher incidence of whooping cough (pertussis) in these...

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Main Authors: Mukkur, Trilochan, Richmond, P.
Format: Journal Article
Published: Omics Publishing Group 2012
Subjects:
Online Access:http://hdl.handle.net/20.500.11937/49313
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author Mukkur, Trilochan
Richmond, P.
author_facet Mukkur, Trilochan
Richmond, P.
author_sort Mukkur, Trilochan
building Curtin Institutional Repository
collection Online Access
description The rate of mortality in children associated with serious infectious diseases is significantly higher in the developing world and in socioeconomically disadvantaged populations in developed industrialized countries. The reasons underpinning the higher incidence of whooping cough (pertussis) in these populations include overcrowding and poor hygiene, poor coverage with available pertussis containing vaccines and waning immunity following immunisation and infection. Two types of vaccines are currently used for vaccinating infants and children. The whole cell pertussis vaccine, the most used vaccine worldwide, consisting of a killed B pertussis strain, origin of which may differ in different countries, is generally given in combination with chemically or genetically inactivated diphtheria and tetanus toxoids [DTwP or DTPw], with or without combination with Haemophilus influenzae type b [Hib], hepatitis B or inactivated polio virus vaccine [IPV], depending upon the vaccine manufacturer.
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spelling curtin-20.500.11937-493132017-03-15T22:56:41Z Development of Affordable Effective Vaccines against Whooping Cough for the Developing World Mukkur, Trilochan Richmond, P. pertussis socioeconomically disadvantaged populations children whooping cough vaccine The rate of mortality in children associated with serious infectious diseases is significantly higher in the developing world and in socioeconomically disadvantaged populations in developed industrialized countries. The reasons underpinning the higher incidence of whooping cough (pertussis) in these populations include overcrowding and poor hygiene, poor coverage with available pertussis containing vaccines and waning immunity following immunisation and infection. Two types of vaccines are currently used for vaccinating infants and children. The whole cell pertussis vaccine, the most used vaccine worldwide, consisting of a killed B pertussis strain, origin of which may differ in different countries, is generally given in combination with chemically or genetically inactivated diphtheria and tetanus toxoids [DTwP or DTPw], with or without combination with Haemophilus influenzae type b [Hib], hepatitis B or inactivated polio virus vaccine [IPV], depending upon the vaccine manufacturer. 2012 Journal Article http://hdl.handle.net/20.500.11937/49313 Omics Publishing Group restricted
spellingShingle pertussis
socioeconomically disadvantaged populations
children
whooping cough
vaccine
Mukkur, Trilochan
Richmond, P.
Development of Affordable Effective Vaccines against Whooping Cough for the Developing World
title Development of Affordable Effective Vaccines against Whooping Cough for the Developing World
title_full Development of Affordable Effective Vaccines against Whooping Cough for the Developing World
title_fullStr Development of Affordable Effective Vaccines against Whooping Cough for the Developing World
title_full_unstemmed Development of Affordable Effective Vaccines against Whooping Cough for the Developing World
title_short Development of Affordable Effective Vaccines against Whooping Cough for the Developing World
title_sort development of affordable effective vaccines against whooping cough for the developing world
topic pertussis
socioeconomically disadvantaged populations
children
whooping cough
vaccine
url http://hdl.handle.net/20.500.11937/49313