Structure/function studies of 5a-reductase.

QR Code

Structure/function studies of 5a-reductase.

This thesis reports structure-function assessments made using site-directed mutagenesis of the human enzyme 5alpha-reductase (5AR), an enzyme crucial for normal masculine development. These assessments utilised the differences between the two forms of the enzyme in affinity for testosterone and sens...

Full description

Bibliographic Details
Main Author:	Baxter, Fiona O.
Format:	Thesis
Language:	English
Published:	Curtin University 2001
Subjects:	5a-reductase stucture-function assessment 5AR
Online Access:	http://hdl.handle.net/20.500.11937/485

Similar Items

Expression of complement C5a receptor and the viability of 4T1 tumor cells following agonist–antagonist treatment
by: Kosni, Nurneqman Nashreq, et al.
Published: (2016)

Glutathione reductase gsr-1 is an essential gene required for Caenorhabditis elegans early embryonic development
by: Mora-Lorca, José Antonio, et al.
Published: (2016)

Targeting thioredoxin reductase in pancreatic cancer
by: Alhadyan, Khaled
Published: (2019)

Would the real arsenate reductase please stand up?
by: Salt, David E.
Published: (2017)

Demonstration of the use of the ICF framework in detailing complex functional deficits after major burn
by: Grisbrook, Tiffany, et al.
Published: (2012)

Reductions using Clostridium sporogenes
by: Mordaka, Pawel Mateusz
Published: (2014)

Flavohemoglobin Hmp, but not its individual domains, confers protection from respiratory inhibition by nitric oxide in Escherichia coli
by: Hernndez-Urza, E., et al.
Published: (2003)

The association between prior statin usage and long-term outcomes after critical care admission
by: Beed, Martin, et al.
Published: (2016)

Cretaceous age, composition, and microstructure of pseudotachylyte in the Otago Schist, New Zealand
by: Barker, S., et al.
Published: (2010)

Assessment of executive functions in people with Human-Immunodeficiency Virus (HIV) infection using the Behavioural Assessment of the Dysexecutive Syndrome: a pilot study
by: Campbell, Amanda
Published: (2010)

Assessing 'functionality' in school mathematics examinations: what does being human have to do with it?
by: Drake, Pat, et al.
Published: (2012)

Association of Statin Use With Disability-Free Survival and Cardiovascular Disease Among Healthy Older Adults
by: Zhou, Z., et al.
Published: (2020)

Heterogeneous excess argon and Neoproterozoic heating in the Usagaran Orogen, Tanzania, revealed by single grain 40Ar/39Ar thermochronology
by: Reddy, Steven, et al.
Published: (2004)

Do statin users adhere to a healthy diet and lifestyle?: the Australian Diabetes, Obesity and Lifestyle Study
by: Johal, Simran, et al.
Published: (2016)

40Ar/39Ar impact ages and time-temperature argon diffusion history of the Bunburra Rockhole anomalous basaltic achondrite
by: Jourdan, Fred, et al.
Published: (2014)

Placental expression of adenosine A2A receptor and hypoxia inducible factor-1 alpha in early pregnancy, term and pre-eclamptic pregnancies: interactions with placental renin-angiotensin system
by: Kurlak, L.O., et al.
Published: (2015)

Mafic dykes intrusive into Pre-Cambrian rocks of the São Luís cratonic fragment and Gurupi Belt (Parnaíba Province), north-northeastern Brazil: Geochemistry, Sr-Nd-Pb-O isotopes, 40Ar/39Ar geochronology, and relationships to CAMP magmatism
by: Klein, E.L., et al.
Published: (2013)

Intercalibration of the Hb3gr 40Ar/39Ar dating standard.
by: Jourdan, Fred, et al.
Published: (2006)

Engineering of a thermostable alcohol dehydrogenase towards imine reduction
by: Nethercott, Alanna Mary
Published: (2018)

40Ar/39Ar ages for deep (~3.3 km) samples from the Hawaii Scientific Drilling Project, Mauna Kea volcano, Hawaii
by: Jourdan, Fred, et al.
Published: (2012)

The 40Ar/39Ar dating technique applied to planetary sciences and terrestrial impacts
by: Jourdan, Fred
Published: (2012)

Timing and duration of the Central Atlantic magmatic province in the Newark and Culpeper basins, eastern U.S.A.
by: Marzoli, A., et al.
Published: (2011)

An inverted-sandwich diuranium μ-η5:η5-cyclo-P5 complex supported by U-P5 δ-bonding
by: Gardner, Benedict M., et al.
Published: (2015)

Targeted suppression of AR-V7 using PIP5K1α inhibitor overcomes enzalutamide resistance in prostate cancer cells
by: Sarwar, Martuza, et al.
Published: (2016)

The bile acid membrane receptor TGR5: a novel pharmacological target in metabolic, inflammatory and neoplastic disorders
by: Stepanov, V., et al.
Published: (2013)

Geochronology and Geochemistry of the Late Cretaceous Basalts in the Jiaolai Basin: Constraints on Lithospheric Thinning and Accretion Beneath North China Craton
by: Kuang, Y., et al.
Published: (2012)

Integrating Augmented Reality with Building Information Modeling: Onsite construction process controlling for liquefied natural gas industry
by: Wang, Xiangyu, et al.
Published: (2013)

Monazite EMP age constraints on deformation along ductile shear zones in the Delhi Fold Belt: implications on Neoproterozoic tectonic evolution of NW India
by: Just, J., et al.
Published: (2011)

Basement control on dyke distribution in Large Igneous Provinces: Case study of the Karoo triple junction.
by: Jourdan, Fred, et al.
Published: (2006)

Application of Collaborative Mobile System in AR-Based Visualization, Data Storage and Manipulation
by: Wang, Xiangyu, et al.
Published: (2013)

Creatine kinase and SLCO1B1 RS4363657 polymorphism in Malaysian dyslipidaemic patients prescribed with statin drugs
by: Meor Anuar Shuhaili, Meor Fairuz Rizal
Published: (2016)

Pain and physical functioning in neuropathic pain: a systematic review of psychometric properties of various outcome measures
by: Meeta, Poonam, et al.
Published: (2016)

Seismic assessment of a heavy-timber frame structure with ring-doweled moment-resisting connections
by: Rodrigues, Leonardo G., et al.
Published: (2017)

40Ar/39Ar ages of the sill complex of the Karoo large igneous province: implications for the Pliensbachian-Toarcian climate change.
by: Jourdan, Fred, et al.
Published: (2008)

Kinematic reworking and exhumation within the convergent Alpine orogen
by: Reddy, Steven, et al.
Published: (2003)

Increased homocysteine levels impair reference memory and reducecortical levels of acetylcholine in a mouse model of vascular cognitive impairment
by: Dam, Kevin, et al.
Published: (2017)

Closed system behaviour of argon in osumilite records protracted high-T metamorphism within the Rogaland–Vest Agder Sector, Norway
by: Blereau, Eleanor, et al.
Published: (2019)

Theoretical study of structural, electronic, and magnetic properties of graphene with adsorbed palladium and vanadium based on density functional theory
by: Abdullahi, Yusuf Zuntu
Published: (2013)

Investigating mid-Ediacaran glaciation and final Gondwana amalgamation using coupled sedimentology and 40Ar/ 39Ar detrital muscovite provenance from the Paraguay Belt, Brazil
by: McGee, B., et al.
Published: (2014)

Laplace approximation of Lauricella functions F A and F D
by: Butler, R.W., et al.
Published: (2015)