Albumin fusion of thioredoxin - The production and evaluation of its biological activity for potential therapeutic applications

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Albumin fusion of thioredoxin - The production and evaluation of its biological activity for potential therapeutic applications

Thioredoxin-1 (Trx) is a redox-active protein with anti-inflammatory effects. The effect of albumin fusion on the pharmacokinetic and pharmacodynamic properties of Trx was evaluated in this study. The findings indicate that the properties of human serum albumin and the fusion protein are comparable....

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Bibliographic Details
Main Authors:	Ikuta, S., Chuang, Victor, Ishima, Y., Nakajou, K., Furukawa, M., Watanabe, H., Maruyama, T., Otagiri, M.
Format:	Journal Article
Published:	Elsevier 2010
Online Access:	http://hdl.handle.net/20.500.11937/48314

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