Molecular dynamics simulation of tau peptides for the investigation of conformational changes induced by specific phosphorylation patterns

The Tau protein plays an important role due to its biomolecular interactions in neurodegenerative diseases. The lack of stable structure and various posttranslational modifications such as phosphorylation at various sites in the Tau protein pose a challenge for many experimental methods that are tra...

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Bibliographic Details
Main Authors: Gandhi, N., Kukic, P., Lippens, G., Mancera, Ricardo
Format: Book Chapter
Published: 2017
Online Access:http://hdl.handle.net/20.500.11937/4821