Genome-wide nucleosome map and cytosine methylation levels of an ancient human genome

Genome-wide nucleosome map and cytosine methylation levels of an ancient human genome

Epigenetic information is available from contemporary organisms, but is difficult to track back in evolutionary time. Here, we show that genome-wide epigenetic information can be gathered directly from next generation sequence reads of DNA isolated from ancient remains. Using the genome sequence dat...

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Bibliographic Details
Main Authors: Pedersen, J., Valen, E., Velazquez, A., Parker, B., Rasmussen, M., Lindgreen, S., Lilje, B., Tobin, D., Kelly, T., Vang, S., Andersson, R., Jones, P., Hoover, C., Tikhonov, A., Prokhortchouk, E., Rubin, E., Sandelin, A., Gilbert, Thomas, Krogh, A., Willerslev, E., Orlando, L.
Format: Journal Article
Published: Cold Spring Harbor Laboratory Press 2014
Subjects:
Cytosine methylation
Nucleosome map
Ancient DNA
Epigenomics
Online Access:http://hdl.handle.net/20.500.11937/48012

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