The Association Between Different Night Shiftwork Factors and Breast Cancer: a Case–Control Study
Background: Research on the possible association between shiftwork and breast cancer is complicated because there are many different shiftwork factors, which might be involved including: light at night, phase shift, sleep disruption and changes in lifestyle factors while on shiftwork (diet, physical...
| Main Authors: | , , , , , , , , , , , , , , |
|---|---|
| Format: | Journal Article |
| Published: |
Nature Publishing Group
2013
|
| Subjects: | |
| Online Access: | http://www.bjcancer.com/ http://hdl.handle.net/20.500.11937/47955 |
| _version_ | 1848757976673812480 |
|---|---|
| author | Fritschi, Lin Erren, T. Glass, D. Girschik, J. Thomson, A. Saunders, C. Boyle, T. El-Zaemey, S. Rogers, P. Peters, S. Slevin, Terry D'Orsogna, A. de Vocht, F. Vermeulen, R. Heyworth, J. |
| author_facet | Fritschi, Lin Erren, T. Glass, D. Girschik, J. Thomson, A. Saunders, C. Boyle, T. El-Zaemey, S. Rogers, P. Peters, S. Slevin, Terry D'Orsogna, A. de Vocht, F. Vermeulen, R. Heyworth, J. |
| author_sort | Fritschi, Lin |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Background: Research on the possible association between shiftwork and breast cancer is complicated because there are many different shiftwork factors, which might be involved including: light at night, phase shift, sleep disruption and changes in lifestyle factors while on shiftwork (diet, physical activity, alcohol intake and low sun exposure).Methods: We conducted a population-based case–control study in Western Australia from 2009 to 2011 with 1205 incident breast cancer cases and 1789 frequency age-matched controls. A self-administered questionnaire was used to collect demographic, reproductive, and lifestyle factors and lifetime occupational history and a telephone interview was used to obtain further details about the shiftwork factors listed above.Results: A small increase in risk was suggested for those ever doing the graveyard shift (work between midnight and 0500 hours) and breast cancer (odds ratio (OR)¼1.16, 95% confidence interval (CI)¼0.97–1.39). For phase shift, we found a 22% increase in breast cancer risk (OR¼1.22, 95% CI¼1.01–1.47) with a statistically significant dose–response relationship (P¼0.04). For the other shiftwork factors, risks were marginally elevated and not statistically significant. Conclusion: We found some evidence that some of the factors involved in shiftwork may be associated with breast cancer but the ORs were low and there were inconsistencies in duration and dose–response relationships. |
| first_indexed | 2025-11-14T09:36:39Z |
| format | Journal Article |
| id | curtin-20.500.11937-47955 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T09:36:39Z |
| publishDate | 2013 |
| publisher | Nature Publishing Group |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-479552017-02-28T01:39:18Z The Association Between Different Night Shiftwork Factors and Breast Cancer: a Case–Control Study Fritschi, Lin Erren, T. Glass, D. Girschik, J. Thomson, A. Saunders, C. Boyle, T. El-Zaemey, S. Rogers, P. Peters, S. Slevin, Terry D'Orsogna, A. de Vocht, F. Vermeulen, R. Heyworth, J. breast cancer case–control shiftwork Background: Research on the possible association between shiftwork and breast cancer is complicated because there are many different shiftwork factors, which might be involved including: light at night, phase shift, sleep disruption and changes in lifestyle factors while on shiftwork (diet, physical activity, alcohol intake and low sun exposure).Methods: We conducted a population-based case–control study in Western Australia from 2009 to 2011 with 1205 incident breast cancer cases and 1789 frequency age-matched controls. A self-administered questionnaire was used to collect demographic, reproductive, and lifestyle factors and lifetime occupational history and a telephone interview was used to obtain further details about the shiftwork factors listed above.Results: A small increase in risk was suggested for those ever doing the graveyard shift (work between midnight and 0500 hours) and breast cancer (odds ratio (OR)¼1.16, 95% confidence interval (CI)¼0.97–1.39). For phase shift, we found a 22% increase in breast cancer risk (OR¼1.22, 95% CI¼1.01–1.47) with a statistically significant dose–response relationship (P¼0.04). For the other shiftwork factors, risks were marginally elevated and not statistically significant. Conclusion: We found some evidence that some of the factors involved in shiftwork may be associated with breast cancer but the ORs were low and there were inconsistencies in duration and dose–response relationships. 2013 Journal Article http://hdl.handle.net/20.500.11937/47955 http://www.bjcancer.com/ Nature Publishing Group restricted |
| spellingShingle | breast cancer case–control shiftwork Fritschi, Lin Erren, T. Glass, D. Girschik, J. Thomson, A. Saunders, C. Boyle, T. El-Zaemey, S. Rogers, P. Peters, S. Slevin, Terry D'Orsogna, A. de Vocht, F. Vermeulen, R. Heyworth, J. The Association Between Different Night Shiftwork Factors and Breast Cancer: a Case–Control Study |
| title | The Association Between Different Night Shiftwork Factors and Breast Cancer: a Case–Control Study |
| title_full | The Association Between Different Night Shiftwork Factors and Breast Cancer: a Case–Control Study |
| title_fullStr | The Association Between Different Night Shiftwork Factors and Breast Cancer: a Case–Control Study |
| title_full_unstemmed | The Association Between Different Night Shiftwork Factors and Breast Cancer: a Case–Control Study |
| title_short | The Association Between Different Night Shiftwork Factors and Breast Cancer: a Case–Control Study |
| title_sort | association between different night shiftwork factors and breast cancer: a case–control study |
| topic | breast cancer case–control shiftwork |
| url | http://www.bjcancer.com/ http://hdl.handle.net/20.500.11937/47955 |