Genome-wide association study in multiple human prion diseases suggests genetic risk factors additional to PRNP

Genome-wide association study in multiple human prion diseases suggests genetic risk factors additional to PRNP

Prion diseases are fatal neurodegenerative diseases of humans and animals caused by the misfolding and aggregation of prion protein (PrP). Mammalian prion diseases are under strong genetic control but few risk factors are known aside from the PrP gene locus (PRNP). No genome-wide association study (...

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Bibliographic Details
Main Authors: Mead, S., Uphill, J., Beck, J., Poulter, M., Campbell, T., Lowe, J., Adamson, G., Hummerich, H., Klopp, N., Ruckert, I., Wichmann, H., Azazu, D., Plagnol, V., Pako, W., Whitfield, J., Alpers, Michael Philip, Whittaker, J., Balding, D., Zerr, I., Kretzschmar, H., Collinge, J.
Format: Journal Article
Published: Oxford University Press 2012
Online Access:http://hdl.handle.net/20.500.11937/47719

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