Targeting the PI3K/Akt signaling pathway in gastric carcinoma: A reality for personalized medicine?
Frequent activation of phosphatidylinositol-3 kinases (PI3K)/Akt/mTOR signaling pathway in gastric cancer (GC) is gaining immense popularity with identification of mutations and/or amplifications of PIK3CA gene or loss of function of PTEN, a tumor suppressor protein, to name a few; both playing a cr...
| Main Authors: | Singh, S., Yap, W., Arfuso, Frank, Kar, S., Wang, C., Cai, W., Dharmarajan, Arunasalam, Sethi, Gautam, Kumar, Alan Prem |
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| Format: | Journal Article |
| Published: |
2015
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| Online Access: | http://hdl.handle.net/20.500.11937/4754 |
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