Mannich and O-Alkylation Reactions of Tetraalkoxyresorcin[4]arenes. The Use of Some Products in Ligand-Assisted Reactions

Mannich and O-Alkylation Reactions of Tetraalkoxyresorcin[4]arenes. The Use of Some Products in Ligand-Assisted Reactions

The measurement of the pKa of racemic tetramethoxyresorcin[4]arenes explains the failure to obtain good yields in attempted Mannich reactions of these substrates under classical reaction conditions. The failure is related to the lack of adequate concentrations of the iminium ions that results from t...

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Bibliographic Details
Main Authors: Buckley, B., Boxhall, J., Page, P., Chan, Y., Elsegood, M., Heaney, H., Holmes, K., Mcildowie, M., McKee, V., McGarth, M., Mocerino, Mauro, Poulton, A., Sampler, E., Skelton, B., White, A.
Format: Journal Article
Published: Wiley-VCH Verlag GMBH 2006
Subjects:
Chiral auxiliaries
- Resorcinarenes
Axial chirality
Mannich reactions
Diastereoselectivity
Configuration determination
Online Access:http://hdl.handle.net/20.500.11937/4752

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