Pigment epithelium-derived factor (PEDF) regulates metabolism and insulin secretion from a clonal rat pancreatic beta cell line BRIN-BD11 and mouse islets

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Pigment epithelium-derived factor (PEDF) regulates metabolism and insulin secretion from a clonal rat pancreatic beta cell line BRIN-BD11 and mouse islets

Pigment epithelium-derived factor (PEDF) is a multifunctional glycoprotein, associated with lipid catabolism and insulin resistance. In the present study, PEDF increased chronic and acute insulin secretion in a clonal rat ß-cell line BRIN-BD11, without alteration of glucose consumption. PEDF also st...

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Bibliographic Details
Main Authors:	Chen, Y., Carlessi, Rodrigo, Walz, N., Cruzat, Vinicius, Keane, Kevin, John, A., Jiang, F., Carnagarin, R., Dass, C., Newsholme, Philip
Format:	Journal Article
Published:	2016
Online Access:	http://hdl.handle.net/20.500.11937/47155

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