Impact of Surface Nano-textured Stainless Steel Prepared by Focused Ion Beam on Endothelial Cell Growth
The modification of stent surfaces with nano-structures has the potential for limiting late stent restenosis. We report here the patterning of 316L austentitic stainless steel with arrays of nano-pits of two nominal diameters: 120 and 180 nm. These nano-textured surfaces were prepared by focused ion...
| Main Authors: | , , , , , , |
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| Format: | Journal Article |
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American Scientific Publishers
2013
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| Online Access: | http://hdl.handle.net/20.500.11937/47130 |
| _version_ | 1848757749896183808 |
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| author | Nazneen, F. Schmidt, M. McLoughlin, E. Petkov, N. Herzog, G. Arrigan, Damien Galvin, P. |
| author_facet | Nazneen, F. Schmidt, M. McLoughlin, E. Petkov, N. Herzog, G. Arrigan, Damien Galvin, P. |
| author_sort | Nazneen, F. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | The modification of stent surfaces with nano-structures has the potential for limiting late stent restenosis. We report here the patterning of 316L austentitic stainless steel with arrays of nano-pits of two nominal diameters: 120 and 180 nm. These nano-textured surfaces were prepared by focused ion beam milling. The influence of the ion beam current on the nano-features was investigated by scanning electron and atomic force microscopies. The optimum ion beam currents were 280 pA for 120 nm nano-pits and 920 pA for 180 nm nano-pits. The depths of the nano-pits formed were (65±24) nm (120 nm) and (84±36) nm (180 nm). This wide distribution of the depths is due to the polycrystalline nature of 316 L stainless steel, which has a strong influence on the milling rates. Endothelial cells were grown in vitro on these substrates for 1, 3 and 5 days. The cells were viable for the duration of the cell culture on the nano-textured substrates. There was no significant difference in the adhesion and the proliferation based on the nano-pit diameter. |
| first_indexed | 2025-11-14T09:33:03Z |
| format | Journal Article |
| id | curtin-20.500.11937-47130 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T09:33:03Z |
| publishDate | 2013 |
| publisher | American Scientific Publishers |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-471302017-09-13T14:28:07Z Impact of Surface Nano-textured Stainless Steel Prepared by Focused Ion Beam on Endothelial Cell Growth Nazneen, F. Schmidt, M. McLoughlin, E. Petkov, N. Herzog, G. Arrigan, Damien Galvin, P. re-stenosis stents in vitro cell studies 316L stainless steel nanostructures The modification of stent surfaces with nano-structures has the potential for limiting late stent restenosis. We report here the patterning of 316L austentitic stainless steel with arrays of nano-pits of two nominal diameters: 120 and 180 nm. These nano-textured surfaces were prepared by focused ion beam milling. The influence of the ion beam current on the nano-features was investigated by scanning electron and atomic force microscopies. The optimum ion beam currents were 280 pA for 120 nm nano-pits and 920 pA for 180 nm nano-pits. The depths of the nano-pits formed were (65±24) nm (120 nm) and (84±36) nm (180 nm). This wide distribution of the depths is due to the polycrystalline nature of 316 L stainless steel, which has a strong influence on the milling rates. Endothelial cells were grown in vitro on these substrates for 1, 3 and 5 days. The cells were viable for the duration of the cell culture on the nano-textured substrates. There was no significant difference in the adhesion and the proliferation based on the nano-pit diameter. 2013 Journal Article http://hdl.handle.net/20.500.11937/47130 10.1166/jnn.2013.7476 American Scientific Publishers restricted |
| spellingShingle | re-stenosis stents in vitro cell studies 316L stainless steel nanostructures Nazneen, F. Schmidt, M. McLoughlin, E. Petkov, N. Herzog, G. Arrigan, Damien Galvin, P. Impact of Surface Nano-textured Stainless Steel Prepared by Focused Ion Beam on Endothelial Cell Growth |
| title | Impact of Surface Nano-textured Stainless Steel Prepared by Focused Ion Beam on Endothelial Cell Growth |
| title_full | Impact of Surface Nano-textured Stainless Steel Prepared by Focused Ion Beam on Endothelial Cell Growth |
| title_fullStr | Impact of Surface Nano-textured Stainless Steel Prepared by Focused Ion Beam on Endothelial Cell Growth |
| title_full_unstemmed | Impact of Surface Nano-textured Stainless Steel Prepared by Focused Ion Beam on Endothelial Cell Growth |
| title_short | Impact of Surface Nano-textured Stainless Steel Prepared by Focused Ion Beam on Endothelial Cell Growth |
| title_sort | impact of surface nano-textured stainless steel prepared by focused ion beam on endothelial cell growth |
| topic | re-stenosis stents in vitro cell studies 316L stainless steel nanostructures |
| url | http://hdl.handle.net/20.500.11937/47130 |