Mannosylation of mutated MBP83-99 peptides diverts immune responses from Th1 to Th2

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Mannosylation of mutated MBP83-99 peptides diverts immune responses from Th1 to Th2

Multiple sclerosis (MS) is an autoimmune demyelinating disease mediated primarily by CD4+ T cells. The design of peptide mutants of disease-associated myelin epitopes to alter immune responses offers a promising avenue for the treatment of MS. We designed and synthesized a number of peptide analogs...

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Bibliographic Details
Main Authors:	Katsara, M., Yuriev, E., Ramsland, Paul, Deraos, G., Tselios, T., Matsoukas, J., Apostolopoulos, V.
Format:	Journal Article
Published:	2008
Online Access:	http://hdl.handle.net/20.500.11937/47052

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