Pharmacokinetically modified human serum albumin based therapeutic design and development

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Pharmacokinetically modified human serum albumin based therapeutic design and development

Human serum albumin (HSA) is synthesized predominantly in the liver, and has an extraordinarily long circulatory half-life (~19 days). Since HSA is responsible for 80% of the colloidal osmotic pressure of plasma, the patients with hypoalbuminemia are typically given a plasma expander to increase the...

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Bibliographic Details
Main Authors:	Taguchi, K., Chuang, Victor, Yamasaki, K., Otagiri, M.
Format:	Book Chapter
Published:	2015
Online Access:	http://hdl.handle.net/20.500.11937/46904

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