Abrogation of STAT3 signaling cascade by zerumbone inhibits proliferation and induces apoptosis in renal cell carcinoma xenograft mouse model

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Abrogation of STAT3 signaling cascade by zerumbone inhibits proliferation and induces apoptosis in renal cell carcinoma xenograft mouse model

Persistent activation of signal transducer and activator of transcription 3 (STAT3) is one of the characteristic features of renal cell carcinoma (RCC) and often linked to its deregulated proliferation, survival, and angiogenesis. In the present report, we investigated whether zerumbone, a sesquiter...

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Bibliographic Details
Main Authors:	Shanmugam, M., Rajendran, P., Li, F., Kim, C., Sikka, S., Siveen, K., Kumar, Alan Prem, Ahn, K., Sethi, G.
Format:	Journal Article
Published:	John Wiley and Sons Inc. 2015
Online Access:	http://hdl.handle.net/20.500.11937/46633

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