Fluid-structure interaction analysis of the left coronary artery with variable branch angulation

The aim of this study is to elucidate the correlation between coronary artery branch angulation, local mechanical and haemodynamic forces at the vicinity of bifurcation. Using a coupled fluid–structure interaction (FSI) modelling approach, five idealized left coronary artery models with various angl...

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Main Authors: Dong, J., Sun, Zhonghua, Inthavong, K., Tu, J.
Format: Journal Article
Published: Taylor & Francis 2014
Subjects:
Online Access:http://hdl.handle.net/20.500.11937/46408
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author Dong, J.
Sun, Zhonghua
Inthavong, K.
Tu, J.
author_facet Dong, J.
Sun, Zhonghua
Inthavong, K.
Tu, J.
author_sort Dong, J.
building Curtin Institutional Repository
collection Online Access
description The aim of this study is to elucidate the correlation between coronary artery branch angulation, local mechanical and haemodynamic forces at the vicinity of bifurcation. Using a coupled fluid–structure interaction (FSI) modelling approach, five idealized left coronary artery models with various angles ranging from 708 to 1108 were developed to investigate the influence of branch angulations. In addition, one CT image-based model was reconstructed to further demonstrate the medical application potential of the proposed FSI coupling method. The results show that the angulation strongly alters its mechanical stress distribution, and the instantaneous wall shear stress distributions are substantially moderated by the arterial wall compliance. As high tensile stress is hypothesized to cause stenosis, the left circumflex side bifurcation shoulder is indicated to induce atherosclerotic changes with a high tendency for wide-angled models.
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institution Curtin University Malaysia
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publishDate 2014
publisher Taylor & Francis
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spelling curtin-20.500.11937-464082017-09-13T13:38:55Z Fluid-structure interaction analysis of the left coronary artery with variable branch angulation Dong, J. Sun, Zhonghua Inthavong, K. Tu, J. branch angulation tensile stress fluid–structure interaction arterial wall compliance left coronary artery wall shear stress The aim of this study is to elucidate the correlation between coronary artery branch angulation, local mechanical and haemodynamic forces at the vicinity of bifurcation. Using a coupled fluid–structure interaction (FSI) modelling approach, five idealized left coronary artery models with various angles ranging from 708 to 1108 were developed to investigate the influence of branch angulations. In addition, one CT image-based model was reconstructed to further demonstrate the medical application potential of the proposed FSI coupling method. The results show that the angulation strongly alters its mechanical stress distribution, and the instantaneous wall shear stress distributions are substantially moderated by the arterial wall compliance. As high tensile stress is hypothesized to cause stenosis, the left circumflex side bifurcation shoulder is indicated to induce atherosclerotic changes with a high tendency for wide-angled models. 2014 Journal Article http://hdl.handle.net/20.500.11937/46408 10.1080/10255842.2014.921682 Taylor & Francis restricted
spellingShingle branch angulation
tensile stress
fluid–structure interaction
arterial wall compliance
left coronary artery
wall shear stress
Dong, J.
Sun, Zhonghua
Inthavong, K.
Tu, J.
Fluid-structure interaction analysis of the left coronary artery with variable branch angulation
title Fluid-structure interaction analysis of the left coronary artery with variable branch angulation
title_full Fluid-structure interaction analysis of the left coronary artery with variable branch angulation
title_fullStr Fluid-structure interaction analysis of the left coronary artery with variable branch angulation
title_full_unstemmed Fluid-structure interaction analysis of the left coronary artery with variable branch angulation
title_short Fluid-structure interaction analysis of the left coronary artery with variable branch angulation
title_sort fluid-structure interaction analysis of the left coronary artery with variable branch angulation
topic branch angulation
tensile stress
fluid–structure interaction
arterial wall compliance
left coronary artery
wall shear stress
url http://hdl.handle.net/20.500.11937/46408