An Electrochemical Sensing Platform Based on Liquid-Liquid Microinterface Arrays Formed in Laser-Ablated Glass Membranes

Arrays of microscale interfaces between two immiscible electrolyte solutions (µITIES) were formed using glass membranes perforated with microscale pores by laser ablation. Square arrays of 100 micropores in 130 µm thick borosilicate glass coverslips were functionalized with trichloro(1H,1H,2H,2H-per...

Full description

Bibliographic Details
Main Authors: Alvarez De Eulate, Eva, Strutwolf, J., Liu, Yang, O'Donnell, Kane, Arrigan, Damien
Format: Journal Article
Published: American Chemical Society 2016
Online Access:http://purl.org/au-research/grants/arc/LE120100026
http://hdl.handle.net/20.500.11937/45849
Description
Summary:Arrays of microscale interfaces between two immiscible electrolyte solutions (µITIES) were formed using glass membranes perforated with microscale pores by laser ablation. Square arrays of 100 micropores in 130 µm thick borosilicate glass coverslips were functionalized with trichloro(1H,1H,2H,2H-perfluorooctyl)silane on one side, to render the surface hydrophobic and support the formation of aqueous-organic liquid-liquid microinterfaces. The pores show a conical shape, with larger radii at the laser entry side (26.5 µm) than at the laser exit side (11.5 µm). The modified surfaces were characterized by contact angle measurements and X-ray photoelectron spectroscopy. The organic phase was placed on the hydrophobic side of the membrane, enabling the array of µITIES to be located at either the wider or narrower pore mouth. The electrochemical behavior of the µITIES arrays were investigated by tetrapropylammonium ion transfer across water-1,6-dichlorohexane interfaces together with finite element computational simulations. The data suggest that the smallest microinterfaces (formed on the laser exit side) were located at the mouth of the pore in hemispherical geometry, while the larger microinterfaces (formed on the laser entry side) were flatter in shape but exhibited more instability due to the significant roughness of the glass around the pore mouths. The glass membrane-supported µITIES arrays presented here provide a new platform for chemical and biochemical sensing systems. © 2016 American Chemical Society.