Genome Expansion and Gene Loss in Powdery Mildew Fungi Reveal Tradeoffs in Extreme Parasitism
Powdery mildews are phytopathogens whose growth and reproduction are entirely dependent on living plant cells. The molecular basis of this life-style, obligate biotrophy, remains unknown. We present the genome analysis of barley powdery mildew, Blumeria graminis f.sp. hordei (Blumeria), as well as a...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Journal Article |
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The American Association for the Advancement of Science
2010
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| Online Access: | http://www.sciencemag.org/content/330/6010/1543.full http://hdl.handle.net/20.500.11937/4569 |
| _version_ | 1848744552996798464 |
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| author | Spanu, P. Abbott, J. Amselem, J. Burgis, T. Soanes, D. Stüber, K. Ver Loren van Themaat, E. Brown, J. Butcher, S. Gurr, S. Lebrun, M. Ridout, C. Schulze-Lefert, P. Talbot, N. Ahmadinejad, N. Ametz, C. Barton, G. Benjdia, M. Bidzinski, P. Bindschedler, L. Both, M. Brewer, M. Cadle-Davidson, L. Cadle-Davidson, M. Collemare, J. Cramer, R. Frenkel, O. Godfrey, D. Harriman, J. Hoede, C. King, B. Klages, S. Kleemann, J. Knoll, D. Koti, P. Kreplak, J. Lopez-Ruiz, Fran Lu, X. Maekawa, T. Mahanil, S. Micali, C. Milgroom, M. Montana, G. Noir, S. O’Connell, R. Oberhaensli, S. Parlange, F. Pedersen, C. Quesneville, H. Reinhardt, R. Rott, M. Sacristán, S. Schmidt, S. Schön, M. Skamnioti, P. Sommer, H. Stephens, A. Takahara, H. Thordal-Christensen, H. Vigouroux, M. Weßling, R. Wicker, T. Panstruga, R. |
| author_facet | Spanu, P. Abbott, J. Amselem, J. Burgis, T. Soanes, D. Stüber, K. Ver Loren van Themaat, E. Brown, J. Butcher, S. Gurr, S. Lebrun, M. Ridout, C. Schulze-Lefert, P. Talbot, N. Ahmadinejad, N. Ametz, C. Barton, G. Benjdia, M. Bidzinski, P. Bindschedler, L. Both, M. Brewer, M. Cadle-Davidson, L. Cadle-Davidson, M. Collemare, J. Cramer, R. Frenkel, O. Godfrey, D. Harriman, J. Hoede, C. King, B. Klages, S. Kleemann, J. Knoll, D. Koti, P. Kreplak, J. Lopez-Ruiz, Fran Lu, X. Maekawa, T. Mahanil, S. Micali, C. Milgroom, M. Montana, G. Noir, S. O’Connell, R. Oberhaensli, S. Parlange, F. Pedersen, C. Quesneville, H. Reinhardt, R. Rott, M. Sacristán, S. Schmidt, S. Schön, M. Skamnioti, P. Sommer, H. Stephens, A. Takahara, H. Thordal-Christensen, H. Vigouroux, M. Weßling, R. Wicker, T. Panstruga, R. |
| author_sort | Spanu, P. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Powdery mildews are phytopathogens whose growth and reproduction are entirely dependent on living plant cells. The molecular basis of this life-style, obligate biotrophy, remains unknown. We present the genome analysis of barley powdery mildew, Blumeria graminis f.sp. hordei (Blumeria), as well as a comparison with the analysis of two powdery mildews pathogenic on dicotyledonous plants. These genomes display massive retrotransposon proliferation, genome-size expansion, and gene losses. The missing genes encode enzymes of primary and secondary metabolism, carbohydrate-active enzymes, and transporters, probably reflecting their redundancy in an exclusively biotrophic life-style. Among the 248 candidate effectors of pathogenesis identified in the Blumeria genome, very few (less than 10) define a core set conserved in all three mildews, suggesting that most effectors represent species-specific adaptations. |
| first_indexed | 2025-11-14T06:03:17Z |
| format | Journal Article |
| id | curtin-20.500.11937-4569 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T06:03:17Z |
| publishDate | 2010 |
| publisher | The American Association for the Advancement of Science |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-45692017-02-28T01:29:31Z Genome Expansion and Gene Loss in Powdery Mildew Fungi Reveal Tradeoffs in Extreme Parasitism Spanu, P. Abbott, J. Amselem, J. Burgis, T. Soanes, D. Stüber, K. Ver Loren van Themaat, E. Brown, J. Butcher, S. Gurr, S. Lebrun, M. Ridout, C. Schulze-Lefert, P. Talbot, N. Ahmadinejad, N. Ametz, C. Barton, G. Benjdia, M. Bidzinski, P. Bindschedler, L. Both, M. Brewer, M. Cadle-Davidson, L. Cadle-Davidson, M. Collemare, J. Cramer, R. Frenkel, O. Godfrey, D. Harriman, J. Hoede, C. King, B. Klages, S. Kleemann, J. Knoll, D. Koti, P. Kreplak, J. Lopez-Ruiz, Fran Lu, X. Maekawa, T. Mahanil, S. Micali, C. Milgroom, M. Montana, G. Noir, S. O’Connell, R. Oberhaensli, S. Parlange, F. Pedersen, C. Quesneville, H. Reinhardt, R. Rott, M. Sacristán, S. Schmidt, S. Schön, M. Skamnioti, P. Sommer, H. Stephens, A. Takahara, H. Thordal-Christensen, H. Vigouroux, M. Weßling, R. Wicker, T. Panstruga, R. Powdery mildews are phytopathogens whose growth and reproduction are entirely dependent on living plant cells. The molecular basis of this life-style, obligate biotrophy, remains unknown. We present the genome analysis of barley powdery mildew, Blumeria graminis f.sp. hordei (Blumeria), as well as a comparison with the analysis of two powdery mildews pathogenic on dicotyledonous plants. These genomes display massive retrotransposon proliferation, genome-size expansion, and gene losses. The missing genes encode enzymes of primary and secondary metabolism, carbohydrate-active enzymes, and transporters, probably reflecting their redundancy in an exclusively biotrophic life-style. Among the 248 candidate effectors of pathogenesis identified in the Blumeria genome, very few (less than 10) define a core set conserved in all three mildews, suggesting that most effectors represent species-specific adaptations. 2010 Journal Article http://hdl.handle.net/20.500.11937/4569 http://www.sciencemag.org/content/330/6010/1543.full The American Association for the Advancement of Science restricted |
| spellingShingle | Spanu, P. Abbott, J. Amselem, J. Burgis, T. Soanes, D. Stüber, K. Ver Loren van Themaat, E. Brown, J. Butcher, S. Gurr, S. Lebrun, M. Ridout, C. Schulze-Lefert, P. Talbot, N. Ahmadinejad, N. Ametz, C. Barton, G. Benjdia, M. Bidzinski, P. Bindschedler, L. Both, M. Brewer, M. Cadle-Davidson, L. Cadle-Davidson, M. Collemare, J. Cramer, R. Frenkel, O. Godfrey, D. Harriman, J. Hoede, C. King, B. Klages, S. Kleemann, J. Knoll, D. Koti, P. Kreplak, J. Lopez-Ruiz, Fran Lu, X. Maekawa, T. Mahanil, S. Micali, C. Milgroom, M. Montana, G. Noir, S. O’Connell, R. Oberhaensli, S. Parlange, F. Pedersen, C. Quesneville, H. Reinhardt, R. Rott, M. Sacristán, S. Schmidt, S. Schön, M. Skamnioti, P. Sommer, H. Stephens, A. Takahara, H. Thordal-Christensen, H. Vigouroux, M. Weßling, R. Wicker, T. Panstruga, R. Genome Expansion and Gene Loss in Powdery Mildew Fungi Reveal Tradeoffs in Extreme Parasitism |
| title | Genome Expansion and Gene Loss in Powdery Mildew Fungi Reveal Tradeoffs in Extreme Parasitism |
| title_full | Genome Expansion and Gene Loss in Powdery Mildew Fungi Reveal Tradeoffs in Extreme Parasitism |
| title_fullStr | Genome Expansion and Gene Loss in Powdery Mildew Fungi Reveal Tradeoffs in Extreme Parasitism |
| title_full_unstemmed | Genome Expansion and Gene Loss in Powdery Mildew Fungi Reveal Tradeoffs in Extreme Parasitism |
| title_short | Genome Expansion and Gene Loss in Powdery Mildew Fungi Reveal Tradeoffs in Extreme Parasitism |
| title_sort | genome expansion and gene loss in powdery mildew fungi reveal tradeoffs in extreme parasitism |
| url | http://www.sciencemag.org/content/330/6010/1543.full http://hdl.handle.net/20.500.11937/4569 |