Functional Anatomy of Phospholipid Binding and Regulation of Phosphoinositide Homeostasis by Proteins of the Sec14 Superfamily

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Functional Anatomy of Phospholipid Binding and Regulation of Phosphoinositide Homeostasis by Proteins of the Sec14 Superfamily

Sec14, the major yeast phosphatidylinositol (PtdIns)/phosphatidylcholine (PtdCho) transfer protein, regulates essential interfaces between lipid metabolism and membrane trafficking from the trans-Golgi network (TGN). How Sec14 does so remains unclear. We report that Sec14 binds PtdIns and PtdCho at ...

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Bibliographic Details
Main Authors:	Schaaf, G., Ortlund, E., Tyeryar, K., Mousley, Carl, Ile, K., Garrett, T., Ren, J., Woolls, M., Raetz, C., Redinbo, M., Bankaitis, V.
Format:	Journal Article
Published:	2008
Online Access:	http://hdl.handle.net/20.500.11937/45619

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