Amino acid supplementation and impact on immune function in the context of exercise
Moderate and chronic bouts of exercise may lead to positive metabolic, molecular, and morphological adaptations, improving health. Although exercise training stimulates the production of reactive oxygen species (ROS), their overall intracellular concentration may not reach damaging levels due to enh...
| Main Authors: | , , |
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| Format: | Journal Article |
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BioMed Central Ltd.
2014
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| Subjects: | |
| Online Access: | http://hdl.handle.net/20.500.11937/45606 |
| _version_ | 1848757333200470016 |
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| author | Cruzat, Vinicius Krause, M. Newsholme, Philip |
| author_facet | Cruzat, Vinicius Krause, M. Newsholme, Philip |
| author_sort | Cruzat, Vinicius |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Moderate and chronic bouts of exercise may lead to positive metabolic, molecular, and morphological adaptations, improving health. Although exercise training stimulates the production of reactive oxygen species (ROS), their overall intracellular concentration may not reach damaging levels due to enhancement of antioxidant responses. However, inadequate exercise training (i.e., single bout of high-intensity or excessive exercise) may result in oxidative stress, muscle fatigue and muscle injury. Moreover, during the recovery period, impaired immunity has been reported, for example; excessive-inflammation and compensatory immunosuppression. Nutritional supplements, sometimes referred to as immuno-nutrients, may be required to reduce immunosuppression and excessive inflammation. Herein, we discuss the action and the possible targets of key immuno-nutrients such as L-glutamine, L-arginine, branched chain amino acids (BCAA) and whey protein. |
| first_indexed | 2025-11-14T09:26:25Z |
| format | Journal Article |
| id | curtin-20.500.11937-45606 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T09:26:25Z |
| publishDate | 2014 |
| publisher | BioMed Central Ltd. |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-456062017-11-08T04:22:54Z Amino acid supplementation and impact on immune function in the context of exercise Cruzat, Vinicius Krause, M. Newsholme, Philip Oxidative stress L-leucine L-glutamine Immunonutrition L-arginine Moderate and chronic bouts of exercise may lead to positive metabolic, molecular, and morphological adaptations, improving health. Although exercise training stimulates the production of reactive oxygen species (ROS), their overall intracellular concentration may not reach damaging levels due to enhancement of antioxidant responses. However, inadequate exercise training (i.e., single bout of high-intensity or excessive exercise) may result in oxidative stress, muscle fatigue and muscle injury. Moreover, during the recovery period, impaired immunity has been reported, for example; excessive-inflammation and compensatory immunosuppression. Nutritional supplements, sometimes referred to as immuno-nutrients, may be required to reduce immunosuppression and excessive inflammation. Herein, we discuss the action and the possible targets of key immuno-nutrients such as L-glutamine, L-arginine, branched chain amino acids (BCAA) and whey protein. 2014 Journal Article http://hdl.handle.net/20.500.11937/45606 10.1186/s12970-014-0061-8 http://creativecommons.org/licenses/by/4.0/ BioMed Central Ltd. fulltext |
| spellingShingle | Oxidative stress L-leucine L-glutamine Immunonutrition L-arginine Cruzat, Vinicius Krause, M. Newsholme, Philip Amino acid supplementation and impact on immune function in the context of exercise |
| title | Amino acid supplementation and impact on immune function in the context of exercise |
| title_full | Amino acid supplementation and impact on immune function in the context of exercise |
| title_fullStr | Amino acid supplementation and impact on immune function in the context of exercise |
| title_full_unstemmed | Amino acid supplementation and impact on immune function in the context of exercise |
| title_short | Amino acid supplementation and impact on immune function in the context of exercise |
| title_sort | amino acid supplementation and impact on immune function in the context of exercise |
| topic | Oxidative stress L-leucine L-glutamine Immunonutrition L-arginine |
| url | http://hdl.handle.net/20.500.11937/45606 |