Nebulized Furosemide for the Management of Dyspnea: Does the Evidence Support Its Use?

Dyspnea is a common and distressing symptom associated with multiple chronic illness and high levels of burden for individuals, their families and health care systems. The subjective nature dyspnea and a poor understanding of pathophysiological mechanisms challenge the clinician in developing manage...

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Main Authors: Newton, Phillip, Davidson, Patricia, Macdonald, P., Ollerton, R., Krum, H.
Format: Journal Article
Published: Elsevier 2008
Subjects:
Online Access:http://hdl.handle.net/20.500.11937/45269
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author Newton, Phillip
Davidson, Patricia
Macdonald, P.
Ollerton, R.
Krum, H.
author_facet Newton, Phillip
Davidson, Patricia
Macdonald, P.
Ollerton, R.
Krum, H.
author_sort Newton, Phillip
building Curtin Institutional Repository
collection Online Access
description Dyspnea is a common and distressing symptom associated with multiple chronic illness and high levels of burden for individuals, their families and health care systems. The subjective nature dyspnea and a poor understanding of pathophysiological mechanisms challenge the clinician in developing management plans. Nebulized furosemide has been identified as a novel approach to dyspnea management. This review summarizes published studies, both clinical and experimental, reporting the use of nebulized furosemide. The search criteria yielded 42 articles published in the period 1988 to 2004. Although nebulized furosemide appeared to have a positive influence on dyspnea and physiological measurements, caution must be taken with the results primarily coming from small-scale clinical trials or observation trials. Despite the limitations of the studies reported, given the range of conditions reporting effectiveness of nebulized furosemide, further investigation of this potential novel treatment of dyspnea is warranted.
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publishDate 2008
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spelling curtin-20.500.11937-452692019-02-19T05:35:12Z Nebulized Furosemide for the Management of Dyspnea: Does the Evidence Support Its Use? Newton, Phillip Davidson, Patricia Macdonald, P. Ollerton, R. Krum, H. chronic disease inhalation drug administration acute disease dyspnea Furosemide Dyspnea is a common and distressing symptom associated with multiple chronic illness and high levels of burden for individuals, their families and health care systems. The subjective nature dyspnea and a poor understanding of pathophysiological mechanisms challenge the clinician in developing management plans. Nebulized furosemide has been identified as a novel approach to dyspnea management. This review summarizes published studies, both clinical and experimental, reporting the use of nebulized furosemide. The search criteria yielded 42 articles published in the period 1988 to 2004. Although nebulized furosemide appeared to have a positive influence on dyspnea and physiological measurements, caution must be taken with the results primarily coming from small-scale clinical trials or observation trials. Despite the limitations of the studies reported, given the range of conditions reporting effectiveness of nebulized furosemide, further investigation of this potential novel treatment of dyspnea is warranted. 2008 Journal Article http://hdl.handle.net/20.500.11937/45269 10.1016/j.jpainsymman.2007.10.017 Elsevier fulltext
spellingShingle chronic disease
inhalation
drug administration
acute disease
dyspnea
Furosemide
Newton, Phillip
Davidson, Patricia
Macdonald, P.
Ollerton, R.
Krum, H.
Nebulized Furosemide for the Management of Dyspnea: Does the Evidence Support Its Use?
title Nebulized Furosemide for the Management of Dyspnea: Does the Evidence Support Its Use?
title_full Nebulized Furosemide for the Management of Dyspnea: Does the Evidence Support Its Use?
title_fullStr Nebulized Furosemide for the Management of Dyspnea: Does the Evidence Support Its Use?
title_full_unstemmed Nebulized Furosemide for the Management of Dyspnea: Does the Evidence Support Its Use?
title_short Nebulized Furosemide for the Management of Dyspnea: Does the Evidence Support Its Use?
title_sort nebulized furosemide for the management of dyspnea: does the evidence support its use?
topic chronic disease
inhalation
drug administration
acute disease
dyspnea
Furosemide
url http://hdl.handle.net/20.500.11937/45269