Gender differences in the relationships between lean body mass, fat mass and peak bone mass in young adults

Summary: The relationships between fat mass and bone mass in young adults are unclear. In 1,183 young Australians, lean body mass had a strong positive relationship with total body bone mass in both genders. Fat mass was a positive predictor of total body bone mass in females, with weaker associatio...

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Main Authors: Zhu, K., Briffa, Kathy, Smith, Anne, Mountain, J., Briggs, Andrew, Lye, S., Pennell, C e, Straker, Leon, Walsh, J.
Format: Journal Article
Published: Springer UK 2014
Subjects:
Online Access:http://hdl.handle.net/20.500.11937/45126
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author Zhu, K.
Briffa, Kathy
Smith, Anne
Mountain, J.
Briggs, Andrew
Lye, S.
Pennell, C e
Straker, Leon
Walsh, J.
author_facet Zhu, K.
Briffa, Kathy
Smith, Anne
Mountain, J.
Briggs, Andrew
Lye, S.
Pennell, C e
Straker, Leon
Walsh, J.
author_sort Zhu, K.
building Curtin Institutional Repository
collection Online Access
description Summary: The relationships between fat mass and bone mass in young adults are unclear. In 1,183 young Australians, lean body mass had a strong positive relationship with total body bone mass in both genders. Fat mass was a positive predictor of total body bone mass in females, with weaker association in males. Introduction: Body weight and lean body mass are established as major determinants of bone mass, but the relationships between fat mass (including visceral fat) and peak bone mass in young adults are unclear. The aim of this study was to evaluate the associations between bone mass in young adults and three body composition measurements: lean body mass, fat mass and trunk-to-limb fat mass ratio (a surrogate measure of visceral fat).Methods: Study participants were 574 women and 609 men aged 19–22 years from the Raine study. Body composition, total body bone mineral content (TBBMC), bone area and areal bone mineral density (TBBMD) were measured using DXA. Results: In multivariate linear regression models with height, lean body mass, fat mass and trunk-to-limb fat mass ratio as predictor variables, lean mass was uniquely associated with the largest proportion of variance of TBBMC and TBBMD in males (semi-partial R2 0.275 and 0.345, respectively) and TBBMC in females (semi-partial R2 0.183). Fat mass was a more important predictor of TBBMC and TBBMD in females (semi-partial R2 0.126 and 0.039, respectively) than males (semi-partial R2 0.006 and 0.018, respectively). Trunk-to limb fat mass ratio had a weak, negative association with TBBMC and bone area in both genders (semi-partial R2 0.004 to 0.034).Conclusions Lean body mass has strong positive relationship with total body bone mass in both genders. Fat mass may play a positive role in peak bone mass attainment in women but the association was weaker in men; different fat compartments may have different effects.
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spelling curtin-20.500.11937-451262017-09-13T14:15:06Z Gender differences in the relationships between lean body mass, fat mass and peak bone mass in young adults Zhu, K. Briffa, Kathy Smith, Anne Mountain, J. Briggs, Andrew Lye, S. Pennell, C e Straker, Leon Walsh, J. Peak bone mass Fatmass Trunk-to-limb fat mass ratio Young adults Raine Study Lean body mass Summary: The relationships between fat mass and bone mass in young adults are unclear. In 1,183 young Australians, lean body mass had a strong positive relationship with total body bone mass in both genders. Fat mass was a positive predictor of total body bone mass in females, with weaker association in males. Introduction: Body weight and lean body mass are established as major determinants of bone mass, but the relationships between fat mass (including visceral fat) and peak bone mass in young adults are unclear. The aim of this study was to evaluate the associations between bone mass in young adults and three body composition measurements: lean body mass, fat mass and trunk-to-limb fat mass ratio (a surrogate measure of visceral fat).Methods: Study participants were 574 women and 609 men aged 19–22 years from the Raine study. Body composition, total body bone mineral content (TBBMC), bone area and areal bone mineral density (TBBMD) were measured using DXA. Results: In multivariate linear regression models with height, lean body mass, fat mass and trunk-to-limb fat mass ratio as predictor variables, lean mass was uniquely associated with the largest proportion of variance of TBBMC and TBBMD in males (semi-partial R2 0.275 and 0.345, respectively) and TBBMC in females (semi-partial R2 0.183). Fat mass was a more important predictor of TBBMC and TBBMD in females (semi-partial R2 0.126 and 0.039, respectively) than males (semi-partial R2 0.006 and 0.018, respectively). Trunk-to limb fat mass ratio had a weak, negative association with TBBMC and bone area in both genders (semi-partial R2 0.004 to 0.034).Conclusions Lean body mass has strong positive relationship with total body bone mass in both genders. Fat mass may play a positive role in peak bone mass attainment in women but the association was weaker in men; different fat compartments may have different effects. 2014 Journal Article http://hdl.handle.net/20.500.11937/45126 10.1007/s00198-014-2665-x Springer UK restricted
spellingShingle Peak bone mass
Fatmass
Trunk-to-limb fat mass ratio
Young adults
Raine Study
Lean body mass
Zhu, K.
Briffa, Kathy
Smith, Anne
Mountain, J.
Briggs, Andrew
Lye, S.
Pennell, C e
Straker, Leon
Walsh, J.
Gender differences in the relationships between lean body mass, fat mass and peak bone mass in young adults
title Gender differences in the relationships between lean body mass, fat mass and peak bone mass in young adults
title_full Gender differences in the relationships between lean body mass, fat mass and peak bone mass in young adults
title_fullStr Gender differences in the relationships between lean body mass, fat mass and peak bone mass in young adults
title_full_unstemmed Gender differences in the relationships between lean body mass, fat mass and peak bone mass in young adults
title_short Gender differences in the relationships between lean body mass, fat mass and peak bone mass in young adults
title_sort gender differences in the relationships between lean body mass, fat mass and peak bone mass in young adults
topic Peak bone mass
Fatmass
Trunk-to-limb fat mass ratio
Young adults
Raine Study
Lean body mass
url http://hdl.handle.net/20.500.11937/45126