Variants in CPT1A, FADS1, and FADS2 are associated with higher levels of estimated plasma and erythrocyte delta-5 desaturases in Alaskan Eskimos

Variants in CPT1A, FADS1, and FADS2 are associated with higher levels of estimated plasma and erythrocyte delta-5 desaturases in Alaskan Eskimos

The delta-5 and delta-6 desaturases (D5D and D6D), encoded by fatty acid desaturase 1 (FADS1) and 2 (FADS2) genes, respectively, are rate-limiting enzymes in the metabolism of ω-3 and ω-6 fatty acids. The objective of this study was to identify genes influencing variation in estimated D5D and D6D ac...

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Bibliographic Details
Main Authors: Voruganti, V., Higgins, P., Ebbesson, S., Kennish, J., Göring, H., Haack, K., Laston, S., Drigalenko, E., Wenger, C., Harris, W., Fabsitz, R., Devereux, R., MacCluer, J., Curran, J., Carless, M., Johnson, M., Moses, Eric, Blangero, J., Umans, J., Howard, B., Cole, S., Comuzzie, A.
Format: Journal Article
Published: 2012
Online Access:http://hdl.handle.net/20.500.11937/44721

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